INCWADANA YEENDABA
Ngemibuzo malunga neemveliso zethu okanye uluhlu lwamaxabiso, nceda ushiye i-imeyile yakho kuthi kwaye siya kuqhagamshelana phakathi kweeyure ezingama-24.
BUZA NGOKUImeko yezothutho
Inokuba kubushushu obuqhelekileyo
Cebisa indlela yokuthumela ngenqanawa
Ngomoya Ngomhlaba Ngolwandle
Imeko yokugcina:
Gcina kwindawo emnyama, umoya ongena ngaphakathi, ubushushu begumbi
Beka ubomi kwishelufa
Malunga neminyaka emi-2
Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)
Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]D20
Siza kuthumela nayiphi na idatha oyifunayo.Ungayibona idatha ngaphambili njengereferensi.
Kwiimveliso ezilungiselelwe wena, sithumela eyona datha intsha emva kokuba iphumile.
I-NT-BOC-N-METHYL-D-PHENYLALANINEDICYCLOHEXYLAMMONI;
Boc-DN-Me-Phe.DHCA;
I-Boc-Nalpha-methyl-D-phenylalanine.DCHA;
i-dicyclohexylamine (R) -2- (tert-butoxycarbonyl (methyl) amino) -3-phenylpropanoate;
N-ALPHA-(BOC)-N-ALPHA-METHYL-D-PHENYLALANINEDICYCLOHEXYLAMINE;
I-N-tert-BOC-N-methyl-D-phenylalaninedicyclohexylammonium;
I-Boc-N-methyl-D-phenylalaninedicyclohexylammoniumsalt≥99%(HPLC)
Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.
I-1kg ukuya kwi-25kg Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.
I-Peptide Synthesis kunye nokuCoca:
I-Boc-DN-Me-Phe-DCHA ingasetyenziselwa njengebhloko yokwakha kwi-peptide synthesis yesigaba esiqinileyo.Ifomu yayo ekhuselweyo ivumela ukongezwa okulandelelanayo kwee-amino acids ngaphandle kweempendulo zecala ezingafunekiyo.Ifom yetyuwa (i-DCHA) ihlala iphakamisa ukunyibilika kunye nokuzinza, iququzelele ukuhlanjululwa kunye nokuhlukaniswa kwe-peptide ephakathi ngexesha lokudibanisa.
I-Stereoselective Synthesis:
Ekubeni i-Boc-DN-Me-Phe-DCHA iqukethe i-D-amino acid, ingasetyenziselwa ukuhlanganiswa kweepeptides kunye ne-chirality ethile (i-D-configuration).Le ndlela yokukhetha i-stereoselective ibalulekile kwiimeko ezithile zebhayoloji apho i-stereochemistry ye-amino acids inokuchaphazela umsebenzi kunye nomsebenzi we-peptides.
Izifundo zebhayoloji:
I-Peptides equkethe i-Boc-DN-Me-Phe-DCHA ingasetyenziselwa njenge-probes kwizifundo ze-biological ukuphanda i-protein-protein interactions, i-receptor binding, okanye inhibition ye-enzyme.I-D-configuration ye-amino acid inokubonelela ngengqiqo ebalulekileyo kwiimfuno zesakhiwo sokuqatshelwa kwezinto eziphilayo kunye nomsebenzi.
Ukufunyanwa kweziyobisi:
Nangona ngaphantsi kwe-peptides e-L-amino acid-based-peptides, i-D-amino acid-equkethe i-peptides ingaba neepropati ezizodwa ze-pharmacological.I-Boc-DN-Me-Phe-DCHA inokuba yinxalenye yomgqatswa weyeza le-peptide kunye nemisebenzi yenoveli yonyango.
Ukusetyenziswa kweNzululwazi yezinto eziphathekayo:
I-Peptides kunye neepolymers eziqulethe iiyunithi ze-Boc-DN-Me-Phe-DCHA zingasetyenziswa kwizinto zokusebenza zesayensi ezifana ne-biocompatible hydrogels, i-scaffolds yobunjineli bezicubu, okanye i-biosensors.Ubuqhetseba obuthile kunye neepropathi zekhemikhali zezi yunithi zinokunikezela ngeempawu ezizodwa okanye zebhayoloji kwimathiriyeli.
Boc-N-Me-L-Phe-OH | ZN-Me-L-Phe-OH | Fmoc-N-Me-L-Phe-OH | BOC-N-Me-D-Phe-OH |
FMOC-N-Me-D-Phe-OH | Boc-N-Me-L-Phe-OH.DCHA | N-Me-D-Phe | Fmoc-N-Me-D-Leu-OH |
Boc-N-Me-DL-Phe-OH | HN-Me-L-Phe-OH | HN-Me-L-Phe.Hcl |
1. Malunga ne-MOQ: Sinokuyilungisa ngokwemfuno yakho.
2. Malunga nesampuli: Isampuli idinga umrhumo wesampuli, onokuthi ube yimpahla yokuqokelela okanye unokuhlawula kuthi kwangaphambili.
3. Iworkshop yokubunjwa, inokwenziwa ngokwezifiso ngokwenani leemodeli.
4. Sinikezela ngeyona nkonzo ibalaseleyo.Iqela lokuthengisa elinamava sele lisebenzela wena.
5. Malunga notshintshiselwano: Nceda uthumele i-imeyile okanye uxoxe nam ngokufanelekileyo.