103898-11-9 Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate

Ukufunyanwa kweziyobisi: I-Tert-Butyl N,N-Bis(2-Hydroxyethyl)I-Carbamate iqhele ukusetyenziswa njengeqela elikhuselayo ekubhaqweni kweziyobisi.Isebenza kunye namaqela asebenzayo afana ne-hydroxyls kunye ne-amines kwiimolekyuli zamachiza, zenza i-tert-butoxycarbonyl (Boc) ekhuselweyo ekhuselweyo.Olu khuselo luvumela ukuhlanganiswa okuzinzileyo kunye nokuhlanjululwa, kunye neqela le-Boc linokususwa phantsi kweemeko ezifanelekileyo ukuveza iqela elisebenzayo lokuqala ukusabela okungaphezulu okanye izifundo zebhayoloji.Ke ngoko, inezicelo ezinokuthi zibe kho ekudibaniseni ichiza, ukuguqulwa kwechiza, kunye nokukhutshwa kwechiza elilawulwayo.

I-Peptide Synthesis: I-Tert-Butyl N,N-Bis(2-Hydroxyethyl)I-Carbamate ikwafumana ukusetyenziswa njengekhonkco kwi-peptide synthesis.Iyakwazi ukusabela kunye neqela le-carboxyl le-amino acids, lenze iibhondi ze-amide ezizinzileyo ukuze zidibanise ezimbini okanye ngaphezulu kwee-amino acids, ukudala amakhonkco e-peptide ngokulandelelana okuthe ngqo kunye nezakhiwo.Le linker isetyenziswa kakhulu kwi-soli-phase peptide synthesis, liquid-phase peptide synthesis, kunye nezinye iindlela.

UPhando lwe-Biochemical: Ngenxa yobume bayo bokubola, i-Tert-Butyl N,N-Bis(2-Hydroxyethyl)I-Carbamate ikwasetyenziswa njengesixhobo kuphando lwe-biochemical.Ngokomzekelo, inokuqeshwa njengekhonkco kwi-synthesis ye-antibody-drug conjugates (ADCs), idibanisa iziyobisi kwii-antibodies zokunikezelwa okujoliswe kuyo kunye nokukhululwa.Ukongezelela, ingasetyenziselwa ukufunda iprotheni-protein kunye neprotheni-ligand interactions, kunye neprotheni yendawo kunye nokusebenza ngaphakathi kweeseli.