iphepha_ibhena

1118767-15-9 Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OSu

1118767-15-9 Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OSu

Inkcazelo emfutshane:

Imbonakalo Umgubo omhlophe ukuya kumhlophe
MF I-C47H82N4O15
MW 943.17
Ubunyulu 98+


Iinkcukacha zeMveliso

Imeko yezothutho
Inokuthuthwa kubushushu obuqhelekileyo.

Cebisa indlela yokuthumela ngenqanawa
ngomoya, ngomhlaba okanye ngolwandle

Imeko yokugcina:
I-2-8 ° C, kufuneka igcinwe kwindawo evaliweyo, ebandayo kwaye engenalanga.

beka ubomi kwishelufa
malunga neminyaka emi-2

Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)

Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]D20  Siza kuthumela nayiphi na idatha oyifunayo.Kodwa kwiimveliso ezenziwe ngokwezifiso, sithumela idatha entsha emva kokuba iphumile.
Ngokuqinisekileyo, unokubona idatha ngaphambili njengereferensi.

I-D-Ls(tfa)-NCA (2)

Izithethantonye

I-Semaglutide ephakathi

 

Ukupakishwa kwangaphakathi

Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

I-1kg ukuya kwi-25kg Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Usetyenziso

Okokuqala, ikhonkco lecala le-semaglutide liyilwe ngokukodwa kwaye lisebenza ngokufanelekileyo, lidlala indima ebalulekileyo kwizicelo zayo zamayeza.Le khonkco yecala, efakwe kwi-26th ye-lysine i-residu ye-peptide chain, ayigcini nje ukunyusa ukuzinza kwesakhiwo se-semaglutide kodwa iququzelele ukusebenzisana kwayo kunye neemolekyuli ezithile ze-biological.

Okwesibini, ikhonkco lecala liquka i-18-carbon fatty diacid chain, eyenziwa ngokudibanisa kwe-glutamic acid, iimolekyuli ezimbini ze-8-amino-3,6-dioxaoctanoic acid (AEEA), kunye ne-octadecanedioic acid.Olu lwakhiwo olukhethekileyo lwekhonkco lwecala lonyusa ubudlelwane be-semaglutide kwi-albumin, ukunciphisa ukucocwa kwezintso kunye nokwandisa isiqingatha sobomi emzimbeni.Lo msebenzi wexesha elide wonyusa isiphumo sonyango kunye nokuqina kwechiza.

Ngaphezu koko, i-pegylation ye-chain chain iphakamisa ukunyibilika kwe-semaglutide kunye nokuhamba, ukunciphisa ukuhluzwa kweentso kunye nokuchithwa kweproteolytic.Olu hlengahlengiso lukwanciphisa i-pyrogenicity yechiza kwaye likhusela ekuhlaselweni kwe-immune system, ukuphucula ukuhanjiswa kweziyobisi kunye nokugcinwa kwindawo ekujoliswe kuyo.

iimveliso ezinxulumene

Fmoc-AEEA-OH Fmoc-AEEA-AEEA-OH H-Glu-OtBU I-Boc-Glu-Otbu(Osu)
Fmoc-L-Ser(tBu)-OH Fmoc-L-Lys-OH·HCl

Kutheni Khetha Thina

1. Malunga ne-MOQ: Sinokuyilungisa ngokwemfuno yakho.
2. Malunga nesampuli: Isampuli idinga umrhumo wesampuli, onokuthi ube yimpahla yokuqokelela okanye unokuhlawula kuthi kwangaphambili.
3. Iworkshop yokubunjwa, inokwenziwa ngokwezifiso ngokwenani leemodeli.
4. Sinikezela ngeyona nkonzo ibalaseleyo.Iqela lokuthengisa elinamava sele lisebenzela wena.
5. Malunga notshintshiselwano: Nceda uthumele i-imeyile okanye uxoxe nam ngokufanelekileyo.


  • Ngaphambili:
  • Okulandelayo:

  • Bhala umyalezo wakho apha kwaye uwuthumele kuthi