iphepha_ibhena

139592-37-3 (Fmoc-Cys-OtBu)2

139592-37-3 (Fmoc-Cys-OtBu)2

Inkcazelo emfutshane:

Imbonakalo Mhlophe ukuya kumgubo oMhlophe
MF I-C44H48N2O8S2
MW 796.99
Ubunyulu 98+


Iinkcukacha zeMveliso

Imeko yezothutho&ecetyiswayo indlela yokuthumela ngenqanawa:
ngomoya, ngolwandle okanye nge-express

Imeko yokugcina:
2-8°C

Ubuncinci boMyinge woMyalelo:
Uthethathethwano

Isiqinisekiso:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC iyafumaneka

I-D-Ls(tfa)-NCA (2)

Izithethantonye

FMoc-L-Cys-OtBu;

(Fmoc-L-Cys-OtBu)2;

(FMOC-CYS-OTBU)2,(DISULFIDEBOND);

(2R)-tert-Butyl2-(((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(((2R)-3-(tert-butoxy)-2-((((1) ,2,3,3a,8,8a-hexahydrocyclopenta[a]inden-8-yl)Methoxy)carbonyl)aMino)-3-oxopropyl)disulfanyl)propanoate;

tert-butyl(2R) -3-[[(2R)-2-(1,2,3,3a,4,8b-hexahydrocyclopenta[a]inden-4-ylmethoxycarbonylamino) -3-tert-butoxy-3-oxo -propyl]disulfanyl]-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoate;

tert-butyl(2R)-3-{[(2R)-3-(tert-butoxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-oxopropyl]disulfanyl} -2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoate;

L-Cystine,N,N'-bis[(9H-fluoren-9-ylmethoxy)carbonyl]-,1,1'-bis(1,1-dimethylethyl)ester

Ukupakishwa kwangaphakathi

Ngokuqhelekileyo zisetyenziselwa ukupakisha umgubo.Yaye anokuthintela ukukhanya kwelanga namanzi ukuba angabi mabi.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

Ibhokisi elukhuni inokukhusela iimveliso zakho ekuqhekekeni kwaye zibe manzi.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Usetyenziso

Okwangoku, i-amino acid derivatives isetyenziswe ngokubanzi njengamachiza okulwa ne-tumor.Iifom zesicelo zezi: (1) njengomphathi wezidakamizwa ezichasene ne-tumor ukunyusa ukunyibilika kweziyobisi, ezifana ne-phenylalanine mustard qi, L-cypamine, LLLL-- Corticine, L-lysine, kunye ne-phenylramine nitrogen mustard ziyabophelela;2(3) Njenge-enzyme inhibitor, indlela yokudibanisa i-pyrimidine nucleic acid, efana ne-N-phosphate acetyl -l-Tianmen citrium yi-inhibitor yenguqu ye-rotorphenols ye-gatemic acid;(4) Njengezinto eziphuma kwi-amino acid ezenza iiseli zomhlaza zibuyele umva, ziphucula ukujoliswa kwazo kwiiseli zethumba.Njengento engapheliyo yobomi, inokwazisa kwiimolekyuli zamachiza, ezinokukhuthaza ukufunxwa kwamachiza ngeeseli, ukunciphisa ubutyhefu bechiza, kwaye ivule iindlela zokufuna amachiza athomalalisayo anetyhefu ephantsi.

iimveliso ezinxulumene

L-Cys-OH (Cys-OH)2 (HD-Cys-OH) 2 (HL-CYS-OTBU)2.HCl
(Boc-L-Cys-Oet)2 (Boc-Cys-OH)2 (Cbz-Cys-OH)2 (Fmoc-Cys-OH)2
Fmoc-L-Cys(Stbu)-OH Fmoc-L-Cys(tBu)-OH I-Fmoc-D-Cys(tBu)-OH I-Fmoc-D-Cys(Acm)-OH

Ukongama

1. Inkonzo yeR&D iyafumaneka
2. Umvelisi oqinisekisiweyo we-ISO, isiqinisekiso somgangatho
I-3.Ikhosi epheleleyo yenkonzo yokulandelela ngexesha lemveliso
4.Ixabiso eliphezulu elisebenzayo
5.Amaxwebhu esiqinisekiso somgangatho anikwe ngokwesicelo somthengi
I-6.Inkonzo enkulu emva kokuthengisa, ukugcina ubudlelwane obusondeleyo kunye nomthengi
I-7.Isixhobo esipheleleyo sokunceda ukunciphisa iindleko zokuthumela ngenqanawa
I-8.Isampuli yamahhala enikezelwa ukujonga umgangatho ngaphambi kwayo nayiphi na intlawulo
9.Ixesha lentlawulo ekuxoxwe ngalo
Abathengi be-10.Assit bajongana nemicimbi yaseTshayina


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