iphepha_ibhena

1491158-62-3 Fmoc-Lys(Pal-Glu-OtBu)-OH

1491158-62-3 Fmoc-Lys(Pal-Glu-OtBu)-OH

Inkcazelo emfutshane:

Imbonakalo Umgubo omhlophe ukuya kumhlophe
MF I-C46H69N3O8
MW 792.06
Ubunyulu 98+


Iinkcukacha zeMveliso

Imeko yezothutho
Inokuba kubushushu obuqhelekileyo

Cebisa indlela yokuthumela ngenqanawa
Ngomoya Ngomhlaba Ngolwandle

Imeko yokugcina:
Gcina kwindawo emnyama, umoya ongena ngaphakathi, ubushushu begumbi

beka ubomi kwishelufa
Malunga neminyaka emi-2

Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)

Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]D20                      

Siza kuthumela nayiphi na idatha oyifunayo.Ungayibona idatha ngaphambili njengereferensi.

Kwiimveliso ezilungiselelwe wena, sithumela eyona datha intsha emva kokuba iphumile.

I-D-Ls(tfa)-NCA (2)

Izithethantonye

I-Fmoc-Ls(Pal-Glu-OtBu)-OH;

N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-[N-(1-oxohexadecyl)-L-gamma-glutamyl]-L-lysine1'-(1,1-dimethylethyl)ester;

(S)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-6-((S)-5-(Tert-Butoxy)-5-Oxo-4-Palmitamidopentanamido)HexanoicAcid;

(9H-Fluoren-9-yl)MethOxy]CarbonyLys(Pal-Glu-OtBu)-OH;

I-N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-epsilon-(N-alpha'-palmitoyl-L-glutamic-acidalpha'-t-butylester)-L-lysine;

Fmoc-L-Lys(Palm-L-Glu-OtBu)-OH;

(2S)-6-[(4S)-5-(tert-butoxy)-4-hexadecanamido-5-oxopentanamido]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoicacid;

L-Lysine,N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-[N-(1-oxohexadecyl)-L-γ-glutamyl]-,1'-(1,1-dimethylethyl)ester

Ukupakishwa kwangaphakathi

Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

I-1kg ukuya kwi-25kg Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Usetyenziso

I-Fmoc-Lys (i-Pal-Glu-OtBu) -OH i-compound enesakhiwo esithile sekhemikhali esifumana ukusetyenziswa okubanzi kwiinkalo ze-bioscience kunye nophando lwamachiza kunye nophuhliso.Ngokukodwa, inokusetyenziswa njengekhonkco le-ADC elinokonakala ukwenzela ukuhlanganiswa kwe-antibody-drug conjugates (ADCs).Ii-ADCs ngamachiza adibanisa iimolekyuli zamachiza kunye nezilwa-buhlungu ngokusebenzisa amakhonkco athile, avumela ukujoliswa okuchanekileyo kunye nonyango lwezifo.Ukongezelela, i-Fmoc-Lys(Pal-Glu-OtBu)-OH isebenza njengekhonkco ye-PROTAC esekelwe kwii-alkyl chain for synthesis of PROTACs.I-PROTACs iimolekyuli ezinokubangela ukuthotywa kweeprotheni ezijoliswe kuyo, ukufezekisa iziphumo zonyango ngokuthobisa iiprotheni ezinxulumene nesifo.

Ngaphaya koko, iinkampani zobuchwephesha bebhayoloji, ezinje ngeShanghai Jinpan Biotechnology Co., Ltd., zibonelela ngolu hlobo lwekhompawundi ukuxhasa umsebenzi wophando lwesayensi yobomi kunye nabaphandi bamayeza.Ezi nkampani ngokuqhelekileyo zijolise ekuboniseni iindlela kunye nemimandla yophando lwezifo, ukubonelela abaphandi ngeemolekyuli eziphezulu ze-bioactive, i-inhibitors, i-agonists, i-inhibitors ethile, iilayibrari ezixubileyo, kunye neeprotheni eziphinda zibuyele.

iimveliso ezinxulumene

Lys(Fmoc)-OH H-Lys(Ac)-OH Ac-Lys-OH Fmoc-L-Lys-OH·HCl
Cbz-L-Lys-OH Fmoc-Lys-Ome·HCl Fmoc-L-Lys(Boc)-OH Fmoc-L-Lys(Fmoc)-OH
Z-DL-Lys(cbz)-OH Cbz-L-Lys(Fmoc)-OH

Kutheni Khetha Thina

1. Malunga ne-MOQ: Sinokuyilungisa ngokwemfuno yakho.
2. Malunga nesampuli: Isampuli idinga umrhumo wesampuli, onokuthi ube yimpahla yokuqokelela okanye unokuhlawula kuthi kwangaphambili.
3. Iworkshop yokubunjwa, inokwenziwa ngokwezifiso ngokwenani leemodeli.
4. Sinikezela ngeyona nkonzo ibalaseleyo.Iqela lokuthengisa elinamava sele lisebenzela wena.
5. Malunga notshintshiselwano: Nceda uthumele i-imeyile okanye uxoxe nam ngokufanelekileyo.


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