INCWADANA YEENDABA
Ngemibuzo malunga neemveliso zethu okanye uluhlu lwamaxabiso, nceda ushiye i-imeyile yakho kuthi kwaye siya kuqhagamshelana phakathi kweeyure ezingama-24.
BUZA NGOKUImeko yezothutho
Inokuba kubushushu obuqhelekileyo
Cebisa indlela yokuthumela ngenqanawa
Ngomoya Ngomhlaba Ngolwandle
Imeko yokugcina:
Gcina kwindawo emnyama, umoya ongena ngaphakathi, ubushushu begumbi
beka ubomi kwishelufa
Malunga neminyaka emi-2
Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)
Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]D20
Siza kuthumela nayiphi na idatha oyifunayo.Ungayibona idatha ngaphambili njengereferensi.
Kwiimveliso ezilungiselelwe wena, sithumela eyona datha intsha emva kokuba iphumile.
I-Pal-Glu(OSu)-OtBu;
I-1-tert-butyl2,5-dioxopyrrolidin-1-yl (2S) -2-hexadecanaMidopentanedioate;
Nε-Hexadecanoyl-L-glutaMicAcidα-t-Butyl-γ-2,5-dioxopyrrolidin-1-yl-diester;
Nε-Palmitoyl-L-glutamicAcid;
I-N-Palmitoyl-L-glutamicacidα-tert-butylesterγ-succinimidylester≥99%(HPLC);
Palmitoyl-Glu(OSu)-OtBu;
Palm-L-Glu(OSu)-OtBu;
Nε-PalMitoyl-L-glutaMicAcidγ-SucciniMidyl-α-tert-butylEster
Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.
I-1kg ukuya kwi-25kg Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.
Ukwenziwa kwePeptide:
Kwintsimi ye-peptide synthesis, i-Pal-Glu (OSu) -OtBu inokusebenza njengebhloko yokwakha okanye i-intermediate kwindibano yamaketanga e-peptide.Inokudityaniswa kulandelelwano kwizikhundla ezithile ukwazisa imisebenzi efunwayo okanye ukukhusela amaqela asebenzayo ngexesha lenkqubo yokudibanisa.
Ukuguqulwa kweprotheyini:
Esi sixhobo sokubuyisela amandla sinokusetyenziselwa ukulungiswa kweprotheyini kwindawo ethile.Ngokujolisa iintsalela ezithile ze-amino acid kwiprotheni, i-Pal-Glu (OSu) -OtBu ingasetyenziselwa ukunamathisela amaqela amatsha asebenzayo okanye iilebula, ukuguqula iiprotheyini zeprotheyini okanye ukuvumela ukufunyanwa kunye nokucocwa kwayo.
I-Organic Synthesis:
Ngokubanzi ngakumbi, kwi-organic synthesis, i-Pal-Glu (OSu) -OtBu inokusebenza njengesibambo sokwenziwa okanye ibhloko yokwakha yokwakha iimolekyuli ezinzima eziphilayo.Iyakwazi ukujongana neekhemikhali ezithile kunye nezinye iziqwenga zezinto eziphilayo, ezikhokelela ekudibaneni kweeathomu ezinezakhiwo ezilungiselelwe kunye nokusebenza.
L-Glu-OH | I-HD-Glu-OH | H-Glu-OtBU | H-Glu(OtBu)-OH |
Boc-L-Glu(Ome)-Ome | Boc-Glu-Otbu |
1. Malunga ne-MOQ: Sinokuyilungisa ngokwemfuno yakho.
2. Malunga nesampuli: Isampuli idinga umrhumo wesampuli, onokuthi ube yimpahla yokuqokelela okanye unokuhlawula kuthi kwangaphambili.
3. Iworkshop yokubunjwa, inokwenziwa ngokwezifiso ngokwenani leemodeli.
4. Sinikezela ngeyona nkonzo ibalaseleyo.Iqela lokuthengisa elinamava sele lisebenzela wena.
5. Malunga notshintshiselwano: Nceda uthumele i-imeyile okanye uxoxe nam ngokufanelekileyo.