INCWADANA YEENDABA
Ngemibuzo malunga neemveliso zethu okanye uluhlu lwamaxabiso, nceda ushiye i-imeyile yakho kuthi kwaye siya kuqhagamshelana phakathi kweeyure ezingama-24.
BUZA NGOKUImeko yezothutho
Inokuba kubushushu obuqhelekileyo
Cebisa indlela yokuthumela ngenqanawa
Ngomoya Ngomhlaba Ngolwandle
Imeko yokugcina:
Gcina kwindawo emnyama, umoya ongena ngaphakathi, ubushushu begumbi
beka ubomi kwishelufa
Malunga neminyaka emi-2
Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)
Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]D20
Siza kuthumela nayiphi na idatha oyifunayo.Ungayibona idatha ngaphambili njengereferensi.
Kwiimveliso ezilungiselelwe wena, sithumela eyona datha intsha emva kokuba iphumile.
I-BENZYLOXYCARBONYL-N-METHYL-L-ALANINE;
I-N-Benzyloxycarbonyl-N-methyl-L-alanine;
2- [benzyloxycarbonyl(methyl)amino]propionicacid;
I-2--[methyl(phenylmethoxycarbonyl)amino]propanoicacid;
ZL-MEALA-OH;
Z-MEALA-OH;
Z-METHYL-L-ALANINE;
ZN-ME-ALANINE
Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.
I-1kg ukuya kwi-25kg Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.
I-Peptide Synthesis: I-Cbz-N-Me-L-Ala-OH isebenza njengebhloko yokwakha kwi-peptide synthesis yesigaba esiqinileyo.Iqela elikhuselayo le-benzoxycarbonyl (Cbz) lizinzisa iqela le-amino le-amino acid ngexesha lenkqubo yokudibanisa, iqinisekisa ukuphendula okuthe ngqo kunye nokusebenza kakuhle.I-N-methylation iguqula iipropati zeekhemikhali ze-alanine, ngaloo ndlela zichaphazela iipropati kunye nemisebenzi yeepeptide ezibangelwayo.
Ukufunyanwa kweziyobisi kunye noPhuhliso: I-Cbz-N-Me-L-Ala-OH kunye ne-peptide conjugates yayo idlala indima ebalulekileyo kuyilo nophuhliso lwamachiza.Ngenxa yezakhiwo zabo zeekhemikhali ezikhethekileyo, banokubonisa imisebenzi ethile ye-pharmacological, ibenza ukuba babe ne-enzyme inhibitors, i-receptor ligands, okanye i-athomu ye-signal transduction.Oku kuvula amathuba okuphuhlisa unyango oluyinoveli okanye ukuphucula ukusebenza kwamachiza asele ekhona.
Izifundo ze-Biological Activity: Ukuqaliswa kwe-N-methylation kwi-Cbz-N-Me-L-Ala-OH kuguqula umsebenzi we-biological we-alanine, ukuguqula ukusebenzisana phakathi kwe-peptides kunye ne-biomolecules ezifana neeprotheni, i-enzymes, okanye i-receptors.Oku kwenza i-Cbz-N-Me-L-Ala-OH ibe sisixhobo esinamandla sokufunda imisebenzi yebhayoloji, imisebenzi yeprotheyini, kunye neendlela zokuhambisa umqondiso.
Uphando lwebhayoloji yoLwakhiwo: I-Cbz-N-Me-L-Ala-OH inokuphinda isetyenziswe kuphando lwebhayoloji yolwakhiwo ukuphanda ukuhambelana, ukuzinza, kunye nokunxibelelana kweepeptides nezinye iiathom zebhayoloji.Olu lwazi lubalulekile ekuqondeni iinkqubo zebhayoloji, iindlela zesifo, kunye neendlela zokuthatha amachiza.
L-ALA | DL-ALA | D-ALA | HN-Me-L-Ala-OH |
N-Me-L-Ala-OMe | N-Me-L-Ala-Ome.Hcl | Boc-N-Me-Ala-OH | Boc-N-Me-DL-Ala-OH |
Fmoc-LN-Me-Ala-OH | Fmoc-N-Me-D-Ala-OH | Cbz-N-Me-D-Ala-OH | HN-Me-L-Ala-OH |
1. Malunga ne-MOQ: Sinokuyilungisa ngokwemfuno yakho.
2. Malunga nesampuli: Isampuli idinga umrhumo wesampuli, onokuthi ube yimpahla yokuqokelela okanye unokuhlawula kuthi kwangaphambili.
3. Iworkshop yokubunjwa, inokwenziwa ngokwezifiso ngokwenani leemodeli.
4. Sinikezela ngeyona nkonzo ibalaseleyo.Iqela lokuthengisa elinamava sele lisebenzela wena.
5. Malunga notshintshiselwano: Nceda uthumele i-imeyile okanye uxoxe nam ngokufanelekileyo.