29022-11-5 Fmoc-Gly-OH

I-29022-11-5 I-Fmoc-gly-OH yenye yezinto eziphakathi kwe-Triptorelin.I-Triptorelin, ekwabizwa ngokuba yi-Triptorelin Acetate Injection, yi-synthetic decapeptide analog ye-gonadotropin-releasing hormone (GnRH), kodwa isebenza ngakumbi kune-GnRH yendalo, kwaye ilawula amanqanaba e-luteinizing hormone (LH), i-follicle evuselela ihomoni (FSH), i-testosterone. (T), kunye ne-estradiol (E2) egazini lomzimba womntu, kwaye isetyenziswe kwiinjongo ezahlukeneyo.Isithako esisebenzayo se-Treprostinil yi-analog yokwenziwa ye-gonadotropin-ekhupha ihomoni (GnRH), ekwabizwa ngokuba yi-tryptophan, dafylline, dabigatran, gonadorelin, ichiza le-antitumor elineziphumo ezifanayo ze-pharmacological njenge-goserelin kunye ne-buserelin, kunye nokuphuculwa kwesakhiwo semolekyuli yendalo. isakhiwo sesithandathu se-levo-glycine sithathelwe indawo yi-dextropro-tryptophan, ebangela ukuba kubekho umphumo ocacileyo osebenzayo kunye ne-plasma ende ye-half-life, kunye nokusebenza okuphezulu.Amandla aphezulu.Emva kwesitofu se-intramuscular, i-pituitary gland iqala ukuvuselela ukukhupha ihomoni ye-luteinizing (LH) kunye ne-chemicalbook follicle stimulating hormone (FSH).Xa i-pituitary gland ingena kwisigaba sokungafanelekanga emva kokuvuselela ixesha elide, ukukhululwa kwe-gonadotropins kunciphisa, ngaloo ndlela kuthoba i-hormone yesini kumanqanaba e-depot.Ezi ziphumo zingasentla ziyabuyiselwa umva.Ulawulo lwe-subcutaneous lufakwe ngokukhawuleza, kunye ne-Tmax ye-15 min kunye nesiphumo esiphezulu se-1 h.Amalungiselelo okukhululwa okuzinzileyo enaliti ye-intramuscular anokugcina ukusebenza kakuhle ngaphezu kwe-28 d.Ngokweklinikhi, isetyenziswa ikakhulu kunyango lwe-endometriosis, umhlaza wesibeleko oxhomekeke kwihomoni, umhlaza wamabele, ukufikisa kokwenyani kwabantwana, kwaye inokusetyenziselwa iindlela ezincedisayo zokuzala.