iphepha_ibhena

30992-29-1 Boc-L-Aib-OH

30992-29-1 Boc-L-Aib-OH

Inkcazelo emfutshane:

Imbonakalo Umgubo omhlophe
MF C9H17NO4
MW 203.24
Ubunyulu 98+


Iinkcukacha zeMveliso

Imeko yezothutho
Inokuba kubushushu obuqhelekileyo

Cebisa indlela yokuthumela ngenqanawa
Ngomoya Ngomhlaba Ngolwandle

Imeko yokugcina:
Gcina kwindawo emnyama, umoya ongena ngaphakathi, ubushushu begumbi

Beka ubomi kwishelufa
Malunga neminyaka emi-2

Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)

Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]D20                      

Siza kuthumela nayiphi na idatha oyifunayo.Ungayibona idatha ngaphambili njengereferensi.

Kwiimveliso ezilungiselelwe wena, sithumela eyona datha intsha emva kokuba iphumile.

I-D-Ls(tfa)-NCA (2)

Izithethantonye

I-BOC-alpha-Methylalanine
N-BOC-2-AMINOISOBUTYRICACID;
N-ALPHA-T-BUTOXYCARBONYL-ALPHA-AMINOISOBUTYRICACID;
I-2-Methyl-2-(tert-butoxycarbonylamino)propionicacid;
N-(tert-Butoxycarbonyl) -2-methylalanine;
N-(tert-Butoxycarbonyl) -2-methyl-L-alanine

Ukupakishwa kwangaphakathi

Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Usetyenziso

I-30992-29-1 i-Boc-L-Aib-OH ingaba ngomnye wabaphakathi be-Anamorelin.

1. Inkxaso yesondlo kunye nokuvuselela ukutya (indima ye-Anamorelin)

Njengeyeza elitsha lonyango lwe-cachexia yomhlaza, i-Anamorelin inokukhuthaza izigulane ukuba zidle izondlo ezininzi ngokuvuselela umdla wokutya.Izigulane ezinomhlaza we-cachexia zihlala zihlupheka ngenxa yokungathandi ukutya, i-anorexia kunye nokudinwa, okukhokelela ekunciphiseni ubunzima kunye nokungondleki.I-Anamorelin yandisa ukutya ngokumodareyitha ukukhululwa kwehomoni yokutya kunye nokuphucula ukuqatshelwa kwesigulane kunye nokuphendula ukutya.Ngokuphucula ukutya okunomsoco, i-Anamorelin inceda ukuphucula imeko yomzimba yesigulane kunye nokwandisa ukuchasana nezifo.

2. Ukukhuselwa kwemisipha kunye nokubuyisela ukusebenza

Izigulane ezine-cachexia zihlala zihambelana nokulahlekelwa kwemisipha kunye nokunciphisa ukusebenza komzimba.I-Anamorelin ikhusela kwaye ikhulise ubunzima be-muscle ngokuphucula ukusebenza kakuhle kweprotheni ye-metabolism, ukwandisa ukulinganisela kweprotheyini ye-protein synthesis kunye nokuthotywa, kunye nokunciphisa i-muscle catabolism ngelixa ikhuthaza ukutya.Ukongezelela, i-Anamorelin iphucula ukukhathala kunye nokuqina, inceda izigulane ezine-cachexia ukuba ziphinde ziphinde zifumane amandla kunye nomsebenzi.

3. Ukuphuculwa kwemeko yengqondo kunye nomgangatho wobomi

I-Cancer cachexia ayichaphazeli nje impilo yomzimba yezigulane, kodwa ichaphazela kakhulu imeko yabo yengqondo kunye nomgangatho wobomi.Umphumo wonyango we-Anamorelin awunqunyelwe kuphela kwinkalo yomzimba, unokuphucula imvakalelo yesigulane kunye nesimo sengqondo ngokuphucula imeko yengqondo.Uphononongo lubonise ukuba izigulane ezisebenzisa i-Anamorelin zinokuphucuka okuphawulekayo kwimeko yengqondo, ukusebenza kwentlalo, ukukhathala kunye nokwaneliseka kobomi.Iphucula kakhulu umgangatho wobomi bezigulane kwaye kwandisa ukuzithemba kwabo ekulweni nomhlaza.

4. Isiphumo sonyango olubanzi kunye nokuphucula ukubuyisela

I-Anamorelin inendima ebalulekileyo kunyango oludibeneyo phakathi kwezigulane zomhlaza ezinesifo esibi.Inokudityaniswa namanye amachiza, ichemotherapy, radiotherapy kunye nolunye unyango ukwenza isiphumo esibanzi.Ngokuphucula imeko yesondlo yesigulane, ubunzima bemisipha kunye nesimo sengqondo, u-Anamorelin unokuphucula umphumo wonyango jikelele.Izigulane ezine-cachexia nazo zingazuza kwinkqubo yokubuyisela.

iimveliso ezinxulumene

Boc-Tyr(Kodwa)-Aib-OH L-Aib-OH 2-Aib-Ome.Hcl
L-Aib-Oet.Hcl Cbz-Aib-Otbu-OH Boc-Aib-Ome-OH
Fmoc-Aib-OH Cbz-Aib-OH

Ukongama

1. Sinikezela ngokwezifiso iimveliso ozifunayo.
2. Umgangatho ophezulu kunye nexabiso elikhuphisanayo linokubonelelwa.
3.Sithembisa ikhosi epheleleyo yenkonzo yokulandelela kuwe.
4. Ikhweshine yomthengisi kunye namaxwebhu obugcisa anokubonelelwa ukuba kucelwe emva kokudibana nesixa esithile.
5. Inkonzo enkulu emva kokuthengisa okanye isiqinisekiso : Nawuphi na umbuzo wakho ungasonjululwa ngokukhawuleza.
6. Ukuthengisa ngaphandle iimveliso ezikhuphisanayo kwaye uzithumele kumazwe angaphandle ngobuninzi obukhulu minyaka le.
I-7.Isampuli yamahhala enikezelwa ukujonga umgangatho ngaphambi kwayo nayiphi na intlawulo.


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