INCWADANA YEENDABA
Ngemibuzo malunga neemveliso zethu okanye uluhlu lwamaxabiso, nceda ushiye i-imeyile yakho kuthi kwaye siya kuqhagamshelana phakathi kweeyure ezingama-24.
BUZA NGOKUImeko yezothutho
Inokuba kubushushu obuqhelekileyo
Cebisa indlela yokuthumela ngenqanawa
Ngomoya Ngomhlaba Ngolwandle
Imeko yokugcina:
Gcina kwindawo emnyama, umoya ongena ngaphakathi, ubushushu begumbi
Beka ubomi kwishelufa
Malunga neminyaka emi-2
Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)
Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]D20
Siza kuthumela nayiphi na idatha oyifunayo.Ungayibona idatha ngaphambili njengereferensi.
Kwiimveliso ezilungiselelwe wena, sithumela eyona datha intsha emva kokuba iphumile.
(S) -2-(tert-butoxycarbonylamino)-3-(1-trityl-1H-imidazol-4-yl)propanoicacid;
(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[1-(triphenylmethyl)-1H-imidazol-4-yl]propanoicacid;
I-Nα-(tert-butyloxy) carbonyl-Nim-triphenylmethyl-L-histidine;
N-Boc-Yakhe(Trt)-OH;
(S)-2-(Boc-aMino)-3-(1-trityl-4-iMidazolyl)propionicacid
Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.
Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.
Uphando lweBiyochemical:
Njenge-reagent ye-biochemical, i-32926-43-5 Boc-L-His (Trt) -OH ingasetyenziselwa kwiprotheni synthesis, reactions enzymatic, kunye nezifundo ze-molecular interaction.
Inokudityaniswa kunye namanye amino acids okanye amacandelo e-peptide ukwenza amatyathanga e-peptide anemisebenzi ethile, ngaloo ndlela ilinganisa imisebenzi yeeprotheni zendalo okanye isebenze njengezixhobo zophando.
Ukufunyanwa kweziyobisi:
32926-43-5 I-Boc-L-His(Trt)-OH idlala indima ebalulekileyo ekufumaneni iziyobisi.Ngenxa yomsebenzi wayo webhayoloji, inokusebenza njengomgqatswa weziyobisi okanye umanduleli weziyobisi kuphuhliso lwenoveli yonyango.
Ukuguqulwa kunye nokulungiswa kwesakhiwo sayo kunokuphucula iipropati zayo ze-pharmacological, ukunciphisa imiphumo emibi, kunye nokuphucula ukuzinza kunye ne-bioavailability kwi-vivo.
I-Organic Synthesis:
Kwi-organic synthesis, i-32926-43-5 i-Boc-L-His (Trt) -OH isebenza njenge-synthetic intermediate yokwakhiwa kwee-molecule ze-organic complex.
I-Boc kunye ne-Trt yokukhusela amaqela kwisakhiwo sayo ivumela ukukhuselwa kwamaqela athile asebenzayo ngexesha lenkqubo yokwenziwa, ukuthintela ukuphendulwa kwecala elingathandekiyo.
Emva kokuba i-synthesis igqityiwe, la maqela akhuselayo anokususwa ngokukhethiweyo ukuze afumane i-molecule efunekayo.
I-Peptide Synthesis:
32926-43-5 Boc-L-His (Trt)-OH isetyenziswa ngokuqhelekileyo njengesiqalo se-amino acid kwi-peptide synthesis yesigaba esiqinileyo.Ngokongezwa ngokuthe ngcembe kwezinye iintsalela ze-amino acid, amatyathanga epeptide anolandelelwano oluthile kunye nezakhiwo zinokudityaniswa.
La matyathanga e-peptide anokusetyenziselwa ukufunda ubudlelwane bokusebenza kweprotheyini, ukuphuhlisa amayeza asekwe kwi-peptide inoveli, okanye asebenze njengezixhobo zokuxilonga.Ngomnye wabaphakathi kwiLiraglutide.
Boc-Gly-Wakhe(Trt)-OH | L-Yakhe-OH | D-Yakhe-OH |
L-His.HCl | D-His-Ome.2Hcl | D-His-OMe.HCl |
L-Yakhe-OMe.2Hcl | L-His-oet.2HCL | L-Yakhe-OMe.2Hcl |
L-Lakhe(trt)-OH | D-Yakhe(trt)-OH | Boc-L-Lakhe-OH |
Boc-Wakhe(Tos).DCHA | Boc-Wakhe(Tos)-OH | Boc-L-Wakhe(Boc)-OH.Dcha |
Boc-Wakhe(Trt)-Gly-OH | Boc-D-His(trt)-OH | Boc-L-Wakhe(Boc)-OH |
Boc-D-Wakhe(Boc)-OH | Fmoc-L-Lakhe-OH | Fmoc-L-Yakhe(Trt)-OH |
1. Sinikezela ngokwezifiso iimveliso ozifunayo.
2. Umgangatho ophezulu kunye nexabiso elikhuphisanayo linokubonelelwa.
3.Sithembisa ikhosi epheleleyo yenkonzo yokulandelela kuwe.
4. Ikhweshine yomthengisi kunye namaxwebhu obugcisa anokubonelelwa ukuba kucelwe emva kokudibana nesixa esithile.
5. Inkonzo enkulu emva kokuthengisa okanye isiqinisekiso : Nawuphi na umbuzo wakho ungasonjululwa ngokukhawuleza.
6. Ukuthengisa ngaphandle iimveliso ezikhuphisanayo kwaye uzithumele kumazwe angaphandle ngobuninzi obukhulu minyaka le.
I-7.Isampuli yamahhala enikezelwa ukujonga umgangatho ngaphambi kwayo nayiphi na intlawulo.