INCWADANA YEENDABA
Ngemibuzo malunga neemveliso zethu okanye uluhlu lwamaxabiso, nceda ushiye i-imeyile yakho kuthi kwaye siya kuqhagamshelana phakathi kweeyure ezingama-24.
BUZA NGOKUImeko yezothutho
Inokuba kubushushu obuqhelekileyo
Cebisa indlela yokuthumela ngenqanawa
Ngomoya Ngomhlaba Ngolwandle
Imeko yokugcina:
Gcina kwindawo emnyama, umoya ongena ngaphakathi, ubushushu begumbi
Beka ubomi kwishelufa
Malunga neminyaka emi-2
Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)
Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]D20
Siza kuthumela nayiphi na idatha oyifunayo.Ungayibona idatha ngaphambili njengereferensi.
Kwiimveliso ezilungiselelwe wena, sithumela eyona datha intsha emva kokuba iphumile.
FMOC-L-METYR(BZL)-OH;
FMOC-METYR(BZL)-OH;
FMOC-N-ALPHA-METHYL-O-BENZYL-L-TYROSINE;
FMOC-N-ME-TYR(BZL)-OH;
FMOC-N-METHYL-O-BENZYL-L-TYROSINE;
N-ALPHA-FMOC-N-ALPHA-METHYL-O-BENZYL-L-TYROSINE;
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ALPHA-METHYL-O-BENZYL-L-TYROSINE;
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-O-BENZYL-L-TYROSINE
Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.
I-1kg ukuya kwi-25kg Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.
I-Fmoc-N-Me-L-Tyr(Bzl)-OH, ekwaziwa ngokuba yi-N-α-(9-fluorenylmethoxycarbonyl)-N-α-methyl-L-tyrosine benzyl ester, yinto ekhuselweyo evela kwi-amino acid edla ngokusetyenziswa kwisiqina. -phase peptide synthesis.Le ngqungquthela idibanisa iqela elikhuselayo le-Fmoc le-amino terminus kunye ne-benzyl (Bzl) ester ekhusela iqela le-phenolic hydroxyl ye-L-tyrosine.
Iqela leFmoc lizinzile kakhulu kwaye linyibilika kwizinyibilikisi zendalo, nto leyo eyenza ukuba ilungele ukuhlanganiswa kwepeptide.Inokususwa ngokulula phantsi kweemeko ze-alkaline, ivumela ukuhlanganisana ngokulandelelana kweepeptides kwizixhaso eziqinileyo.I-benzyl ester, ngakolunye uhlangothi, ikhusela iqela le-phenolic hydroxyl ye-L-tyrosine, ukukhusela ukuphendula okungafunekiyo ngexesha lenkqubo yokudibanisa.
Ukusetyenziswa okuphambili kwe-Fmoc-N-Me-L-Tyr (Bzl)-OH kukulungiselela i-peptides equkethe i-L-tyrosine.Ngokuzisa le amino acid ephuma kulandelelwano lwepeptide, abaphandi banokufaka i-L-tyrosine kunye ne-amino kunye ne-phenolic hydroxyl amaqela akhuselweyo.Oku kuvumela ulawulo oluchanekileyo phezu kwesakhiwo se-peptide kwaye iququzelele ukuqaliswa kwamanye ama-amino acids kunye nokuguqulwa kwizikhundla ezithile ngaphakathi kwekhonkco le-peptide.
I-L-Tyrosine yi-amino acid ebalulekileyo kwisondlo somntu kwaye inemisebenzi eyahlukeneyo yebhayoloji, kubandakanywa nokusebenza njenge-precursor ye-neurotransmitters kunye nokuveliswa kwe-melanin.Iipeptide eziqulethe i-L-tyrosine zingasetyenziselwa ukufunda le misebenzi okanye ukuphuhlisa amachiza amatsha okanye ii-arhente zonyango.
N-Me-Tyr(Me)-OH.HCl | Boc-N-Me-L-Tyr(tbu)-OH | Fmoc-N-Me-L-Tyr(tBu)-OH | Cbz-N-Me-Tyr(tbu)-OH |
Fmoc-N-Me-D-Tyr(tBu)-OH | Boc-N-Me-L-Tyr(bzl)-OH | FMOC-N-Me-D-Tyr(me)-OH | Boc-N-Me-D-Tyr(bzl)-OH |
1. Malunga ne-MOQ: Sinokuyilungisa ngokwemfuno yakho.
2. Malunga nesampuli: Isampuli idinga umrhumo wesampuli, onokuthi ube yimpahla yokuqokelela okanye unokuhlawula kuthi kwangaphambili.
3. Iworkshop yokubunjwa, inokwenziwa ngokwezifiso ngokwenani leemodeli.
4. Sinikezela ngeyona nkonzo ibalaseleyo.Iqela lokuthengisa elinamava sele lisebenzela wena.
5. Malunga notshintshiselwano: Nceda uthumele i-imeyile okanye uxoxe nam ngokufanelekileyo.