I-China 583840-03-3 SORAFENIB N-OXIDE uMvelisi kunye neFactory |Jiayinglai

583840-03-3 SORAFENIB N-OXIDE

Inkcazelo emfutshane:

Imbonakalo	Okumhlophe okuqinileyo
MF	I-C21H16ClF3N4O4
MW	480.82
Ubunyulu	98+

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Imeko yezothutho&ecetyiswayo indlela yokuthumela ngenqanawa:
ngomoya, ngolwandle okanye nge-express

Imeko yokugcina:
2-8°C

Ubuncinci boMyinge woMyalelo:
Uthethathethwano

Isiqinisekiso:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC iyafumaneka

Izithethantonye

I-Sorafenibimpurity23/SorafenibN-Oxide/4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-2-(methylcarbamoyl)pyridine1-oxide;

I-SORAFENIBN-OXIDE;

4-[4-[[[[4-Chloro-3-(trifluoroMethyl)phenyl]aMino]carbonyl]aMino]phenoxy]-N-Methyl-2-pyridinecarboxaMide1-Oxide;

I-SorafenibImpurity27(SorafenibN-Oxide);

I-2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-,1-oxide;

4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-2-(methylcarbamoyl)pyridine1-oxide;

Sorafenibimpurities172;

Sorafenibimpurities11

Ukupakishwa kwangaphakathi

Ngokuqhelekileyo zisetyenziselwa ukupakisha umgubo.Yaye anokuthintela ukukhanya kwelanga namanzi ukuba angabi mabi.

ukupakisha kwangaphandle

Ibhokisi elukhuni inokukhusela iimveliso zakho ekuqhekekeni kwaye zibe manzi.

Usetyenziso

Kwikhemistri kunye nenzululwazi yemathiriyeli, ukungcola zizinto zekhemikhali ngaphakathi kwisixa esivaliweyo solwelo, igesi, okanye okuqinileyo, okwahlukileyo kukwakheka kweekhemikhali zemathiriyeli okanye ikhompawundi.Okokuqala, ikhemikhali esulungekileyo kufuneka ibonakale i-thermodynamically kwisigaba esinye sekhemikhali kwaye inokubonakaliswa ngedayagram yecandelo elinye.Okwesibini, xa sithetha ngenyani, umchiza osulungekileyo kufuneka ungqineke unobumbano (okt, awusayi kubonisa lutshintsho lweepropati emva kokwenziwa kweenkqubo ezininzi ezilandelelanayo zohlalutyo lwemichiza).Ikhemikhali ecocekileyo egqibeleleyo iya kudlula yonke imizamo kunye neemvavanyo zokwahlula ngakumbi kunye nokucoca.Okwesithathu, kwaye apha sigxininise kwinkcazo yekhemikhali eqhelekileyo, akufanele iqulethe naluphi na uhlobo lweentlobo zemichiza.Enyanisweni, akukho 100% ngokupheleleyo iikhompawundi zemichiza ecocekileyo, njengoko kusoloko kukho ungcoliseko oluthile.Enyanisweni, njengoko imida yokubona kwikhemistri yohlalutyo iyancipha, inani lokungcola elifunyenweyo livame ukunyuka.

Ukungcola kuyenzeka ngokwemvelo okanye kongezwe ngexesha lokudityaniswa kweekhemikhali okanye imveliso yorhwebo.Ngexesha lemveliso, ukungcola kunokuba ngabom, ngengozi, ngokungenakuthintelwa, okanye ngokuzenzekelayo kongezwe kwinto.

Amanqanaba okungcola kwimathiriyeli achazwa ngokubanzi ngokwemigaqo ehambelanayo.Imigangatho isekwe yimibutho eyahlukeneyo ezama ukuchaza amanqanaba avumelekileyo okungcola okwahlukeneyo kwimveliso eyenziweyo.Ukuthetha ngokuthe ngqo, ke inqanaba lokucoceka kwezinto kunokuchazwa nje ngokuba nyulu ngakumbi okanye ngaphantsi kwezinye izinto.

Ukongama

1. Inkonzo yeR&D iyafumaneka
2. Umvelisi oqinisekisiweyo we-ISO, isiqinisekiso somgangatho
I-3.Ikhosi epheleleyo yenkonzo yokulandelela ngexesha lemveliso
4.Ixabiso eliphezulu elisebenzayo
5.Amaxwebhu esiqinisekiso somgangatho anikwe ngokwesicelo somthengi
I-6.Inkonzo enkulu emva kokuthengisa, ukugcina ubudlelwane obusondeleyo kunye nomthengi
I-7.Isixhobo esipheleleyo sokunceda ukunciphisa iindleko zokuthumela
I-8.Isampuli yamahhala enikezelwa ukujonga umgangatho ngaphambi kwayo nayiphi na intlawulo
9.Ixesha lentlawulo ekuxoxwe ngalo
Abathengi be-10.Assit bajongana nemicimbi yaseTshayina