Boc-Wakhe(Boc)-Aib-OH

I-Peptide Synthesis kunye nokuguqulwa: i-Boc-His (Boc) -Aib-OH inokusebenza njengebhloko yokwakha ngaphakathi kwekhonkco le-peptide, eyenza ukwakhiwa kweepeptide ngokulandelelana okuthe ngqo kunye nemisebenzi ngokudibanisa namanye amino acids okanye amacandelo e-peptide.Ezi peptides zenziwe ngokwesiko zinezicelo ezibanzi ekufunyanweni kweziyobisi, kuphando lwebhayoloji, kunye nezinye iindawo ezinxulumeneyo.
Ukunikezelwa kobukho be-histidine (Yakhe) kunye ne-α-aminoisobutyric acid (Aib), iimpawu ezikhethekileyo zala ma-amino acids zinika i-Boc-His (Boc) -Aib-OH ngendima ebalulekileyo kwiindlela ezithile ze-peptide.Banokonyusa uzinzo kunye nomsebenzi webhayoloji weepeptides.
UPhando lweBiological Activity kunye noLawulo:I-Boc-His(Boc)-Aib-OH inomsebenzi webhayoloji engokwemvelo, iyenza ibe sisixhobo esixabisekileyo kwizifundo zebhayoloji.Abaphandi banokuyifaka kwiinkqubo zebhayoloji ukuze bajonge impembelelo yayo kwiinkqubo zeselula, ngaloo ndlela befumana ukuqonda okunzulu kwiinkqubo ze-physiological and pathological.
Ngokuxhaphaza iqela le-imidazole le-histidine kunye nesakhiwo esiyingqayizivele se-α-aminoisobutyric acid, i-Boc-His (Boc) -Aib-OH inokuchaphazela ukusebenzisana kwayo kunye ne-receptors okanye ezinye i-biomolecules, ilawula iimpendulo ezithile ze-biological okanye iindlela zokudlulisa umqondiso.
Uyilo lweDrugs kunye noPhuhliso: i-Boc-His(Boc)-Aib-OH ibambe ixabiso elinokubakho lesicelo kwinkalo yokufunyanwa kweziyobisi.Ukuguqulwa kwesakhiwo okanye ukulungelelaniswa kunokukhokelela kwiikhompawundi kunye nemisebenzi ethile ye-pharmacological, esebenza njengamachiza abaviwa ukuze kuphandwe ngakumbi kunye nophuhliso.
Ukuqwalasela iipropati ezinokuthi ze-ion chelating ze-imidazole yeqela le-histidine kunye ne-biocompatibility ye-α-aminoisobutyric acid, i-Boc-His (Boc) -Aib-OH inokuthi yenzelwe ukuphuhliswa kweziyobisi ezintsha ezijoliswe kwizifo ezithile okanye iithagethi zezinto eziphilayo.
Uphando lwe-Biochemical kunye ne-Biophysical: i-Boc-His (i-Boc) -i-Aib-OH inokusebenza njengekhompawundi yomzekelo wokufunda iindlela zokusebenzisana phakathi kwe-peptides kunye ne-biomolecules ezifana neeprotheni kunye ne-DNA, kunye nokusonga kwe-peptide kunye nokuzinza ngaphakathi kweenkqubo zebhayoloji.

Ngophando kunxibelelwano lwayo kunye ne-biomolecules eyahlukeneyo, ukuqonda okunzulu kweempawu zebhayoloji kunye nemisebenzi yeepeptides inokufunyanwa.