INCWADANA YEENDABA
Ngemibuzo malunga neemveliso zethu okanye uluhlu lwamaxabiso, nceda ushiye i-imeyile yakho kuthi kwaye siya kuqhagamshelana phakathi kweeyure ezingama-24.
BUZA NGOKUImeko yezothutho
Inokuthuthwa kubushushu obuqhelekileyo.
Cebisa indlela yokuthumela ngenqanawa
ngomoya, ngomhlaba okanye ngolwandle
Imeko yokugcina:
I-2-8 ° C, kufuneka igcinwe kwindawo evaliweyo, ebandayo kwaye engenalanga.
beka ubomi kwishelufa
malunga neminyaka emi-2
Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)
Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]D20 Siza kuthumela nayiphi na idatha oyifunayo.Kodwa kwiimveliso ezenziwe ngokwezifiso, sithumela idatha entsha emva kokuba iphumile.
Ngokuqinisekileyo, unokubona idatha ngaphambili njengereferensi.
Fmoc-L-Gln(Trt)-Aib-OH
Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.
I-1kg ukuya kwi-25kg Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.
Ukusetyenziswa kwe-Fmoc-L-Gln(Trt)-Aib-OH yahlukile kwaye ibambe ixabiso elibalulekileyo kwiinkalo ezahlukeneyo.Nantsi inkcazo yezicelo zayo eziphambili:
I-Peptide Synthesis:
I-Fmoc-L-Gln(Trt)-Aib-OH isebenza njengebhloko yokwakha ebalulekileyo kwi-peptide synthesis yesigaba esiqinileyo.Indibaniselwano yayo ekhethekileyo ye-Fmoc kunye namaqela okhuseleko e-Trt iqinisekisa uzinzo kunye nokunyibilika, okwenza ukuba indibano echanekileyo yamatyathanga e-peptide.
Ukufakwa kwe-amino acid engeyiyo yendalo i-Aib (i-α-aminoisobutyric acid) ivumela ukuqaliswa kokulandelelana okukhethekileyo kunye nemisebenzi enokubakho yezinto eziphilayo.
Ubunjineli beProtheyini kunye noHlengahlengiso:
Le derivative ingasetyenziselwa ukudibanisa okanye iiprotheyini ziguqule ngokulandelelana okuthe ngqo kwe-amino acid, eyenza ufundo lwesakhiwo seprotheni kunye nomsebenzi.
Ukuqaliswa kwe-Aib kunokuphucula iimpawu zeprotheni ezifana nokuzinza, umsebenzi we-enzymatic, okanye ukusebenzisana nezinye iiamolekyu.
Ukufunyanwa kweziyobisi kunye noYilo:
Iipeptide eziqulethe i-Fmoc-L-Gln(Trt)-Aib-OH zinokujongiwa amandla azo onyango, oko kubenza babe ngabaviwa abaxabisekileyo kuphuhliso lwamachiza.
Ulandelelwano oluthile lwe-amino acid kunye nobukho be-Aib bunokuphucula ubudlelwane obubophezelayo kunye nokukhetha kwiimolekyuli ezijoliswe kuyo.
Ii-Biological Probes kunye nee-Arhente zoMfanekiso:
Iimpawu ezizodwa ze-Fmoc-L-Gln (Trt)-Aib-OH zenza ukuba zilungele ukuphuhlisa i-biological probes kunye ne-imaging agents.
Ezi probes zingasetyenziselwa ukufunda iinkqubo zebhayoloji, ukufumanisa ukusebenzisana kweemolekyuli, okanye uncedo ekuxilongeni kwangaphambili kwezifo.
IiNjongo zoPhando kunye nezeMfundo:
Ngenxa yokulungelelaniswa kwayo kunye neempawu ezizinzileyo, i-Fmoc-L-Gln (Trt) -Aib-OH ihlala iqeshwe kuphando olusisiseko kunye novavanyo lwezemfundo kwi-biochemistry kunye ne-organic chemistry.
Inceda abafundi kunye nabaphandi ukuba baqonde ngcono kwaye balawule imigaqo kunye nobuchule be-peptide synthesis kunye nobunjineli beprotheyini.
Boc-Gly-Ile-OH | L-Ile-OH | D,L-Ile-OH | N-Me-L-Ile-OH |
Boc-L-Ile-OH | Fmoc-L-Ile-OH | Fmoc-LN-Me-Ile-OH | Cbz-L-Ile-OH |
2-Aib-Ome.Hcl | Boc-L-Aib-OH | Fmoc-L-Aib-OH |
1. Malunga ne-MOQ: Sinokuyilungisa ngokwemfuno yakho.
2. Malunga nesampuli: Isampuli idinga umrhumo wesampuli, onokuthi ube yimpahla yokuqokelela okanye unokuhlawula kuthi kwangaphambili.
3. Iworkshop yokubunjwa, inokwenziwa ngokwezifiso ngokwenani leemodeli.
4. Sinikezela ngeyona nkonzo ibalaseleyo.Iqela lokuthengisa elinamava sele lisebenzela wena.
5. Malunga notshintshiselwano: Nceda uthumele i-imeyile okanye uxoxe nam ngokufanelekileyo.