iphepha_ibhena

122235-70-5 BOC-DAP(FMOC)-OH

122235-70-5 BOC-DAP(FMOC)-OH

Inkcazelo emfutshane:

Imbonakalo Mhlophe ukuya kumgubo oMhlophe
MF I-C23H26N2O6
MW 426.46
Ubunyulu 98+


Iinkcukacha zeMveliso

Imeko yezothutho&ecetyiswayo indlela yokuthumela ngenqanawa:
ngomoya, ngolwandle okanye nge-express

Imeko yokugcina:
2-8°C

Ubuncinci boMyinge woMyalelo:
Uthethathethwano

Isiqinisekiso:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC iyafumaneka

I-D-Ls(tfa)-NCA (2)

Izithethantonye

Boc-3-(Fmoc-amino)-L-alanine,Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionicacid;

I-NALPHA-tert-Butoxycarbonyl-NB-9-fluorenylmethoxycarbonyl-L-2,3-diaminopropi;

N-.ALPHA.-BOC-N-.BETA.-FMOC-L-2,3-DIAMIOPROPIONICACID;

I-N-Boc-N-Fmoc- (S) -2,3-diaminopropionicacid;

I-N-α-Boc-N-β-Fmoc-L-2,3-diamiopropionicacid;

(S) -2,3-Diaminopropanoicacid,N2-BOC,N3-FMOCekhuselweyo;

3-[(9H-Fluoren-9-ylmethoxycarbonyl)amino]-L-alanine,N-BOCKhuselweyo;

Boc-Dapa(FMoc)-OH

Ukupakishwa kwangaphakathi

Ngokuqhelekileyo zisetyenziselwa ukupakisha umgubo.Yaye anokuthintela ukukhanya kwelanga namanzi ukuba angabi mabi.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

Ibhokisi elukhuni inokukhusela iimveliso zakho ekuqhekekeni kwaye zibe manzi.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Usetyenziso

I-amino acids ekhusela kabini ikakhulu ibandakanya i-D-lys-OH equlathe amaqela e-amino ecala kunye nekhonkco elisecaleni eliqulathe ikhonkco.pukujikelezwa kwe-L-Rag-OH.Kwiqela le-AA-amin, isicwangciso sokukhusela i-FMOC sisamkelwa, kwaye umalume wesibini we-carbonate-carbonate usetyenziswa kwi-chain chain.I-Tibon ifakwe kwiqela lemibhobho ye-oksijeni ukuze ikhusele iFu Fu 5 ~ Sulfidal ukukhusela.Ngenxa yokuba kukho amanyathelo amaninzi okudibanisa ezi zimbini ze-amino acids, impendulo ephambili kwimpendulo ephambilisI-teps yenza imifuniselo yokwandisa into enye.Ukukhuselwa kwe-D-LYS-OH ikakhulu kuqwalaselwa ixesha elichaphazela isizukulwana sobheduiubushushu, kunye nexesha lokukhupha ubhedu.Ukukhuselwa kwe-L-Rag-OH ikakhulu kuqwalaselwa ukulungiswa kwe-Z-RG-OH. Ngelo xesha, ubushushu be-ZL-Rag (PBF) -OH ring yetyuwa ye-ammonia, kunye nomlinganiselo we-catalyst xa i-hydrogen ihlanganiswe ne-Z,tUxinzelelo lwakhe, ubushushu kunye nexesha lokuphendula lifumene imveliso elungileyo ngokusebenzisa imifuniselo yokuphucula.

Ngexesha lenkqubo yokusabela, inkqubo yokujonga i-TL.C yokufumanisa ithathwa ngokuyintloko, kwaye iimeko ze-crystallization zemveliso ziphuculwe.

Ukucoceka kwemveliso kulinganiswa ne-high-efficiency liquid chromatography, kwaye ukucoceka kwemveliso kufikelele ngaphezu kwe-95.0%.Ukongeza kwiimpawu eziqhelekileyo zomzimba eziqhelekileyo, kwakhonaiukuquka infrared spectrum, mass spectrum okanye hydrogen spectrum.

iimveliso ezinxulumene

Boc-D-Dap(Boc).DCHA Boc-Dap(Boc)-OH.DCHA I-Boc-D-Dap(Fmoc)-OH Boc-Dap(Cbz)-OH
Boc-D-Dap(Cbz)-OH Fmoc-L-Dap(Fmoc)-OH Fmoc-L-Dap(Cbz)-OH Fmoc-D-Dap(cbz)
Cbz-D-Dap(BOC)-OH Cbz-L-Dap(Fmoc)-OH

 

 

Ukongama

1. Inkonzo yeR&D iyafumaneka
2. Umvelisi oqinisekisiweyo we-ISO, isiqinisekiso somgangatho
I-3.Ikhosi epheleleyo yenkonzo yokulandelela ngexesha lemveliso
4.Ixabiso eliphezulu elisebenzayo
5.Amaxwebhu esiqinisekiso somgangatho anikwe ngokwesicelo somthengi
I-6.Inkonzo enkulu emva kokuthengisa, ukugcina ubudlelwane obusondeleyo kunye nomthengi
I-7.Isixhobo esipheleleyo sokunceda ukunciphisa iindleko zokuthumela ngenqanawa
I-8.Isampuli yamahhala enikezelwa ukujonga umgangatho ngaphambi kwayo nayiphi na intlawulo
9.Ixesha lentlawulo ekuxoxwe ngalo
Abathengi be-10.Assit bajongana nemicimbi yaseTshayina


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