China 2013-12-9 D (-)-Norvaline Manufacturer kunye neFactory |Jiayinglai

2013-12-9 D(-)-Norvaline

Inkcazelo emfutshane:

Imbonakalo	Mhlophe ukuya kuMhlophe
MF	C5H11NO2
MW	117.15
Ubunyulu	98+

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Imeko yezothutho&ecetyiswayo indlela yokuthumela ngenqanawa:
ngomoya, ngolwandle okanye nge-express

Imeko yokugcina:
2-8°C

Ubuncinci boMyinge woMyalelo:
Uthethathethwano

Isiqinisekiso:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC iyafumaneka

Izithethantonye

I-HD-NVA-OH;

I-HD-NHCH[CH3(CH2)2]-COOH;

I-HD-NORVALINE;

I-HD-APE(2)-OH;

D-Nval-OH;

I-HD-2-AMINOVALERIC ACID;

D-Nva-OH;

D-Nval

Ukupakishwa kwangaphakathi

Ngokuqhelekileyo zisetyenziselwa ukupakisha umgubo.Yaye anokuthintela ukukhanya kwelanga namanzi ukuba angabi mabi.

ukupakisha kwangaphandle

Ibhokisi elukhuni inokukhusela iimveliso zakho ekuqhekekeni kwaye zibe manzi.

Usetyenziso

Ingasetyenziselwa ukwenza i-D-Glu.Iintlobo ngeentlobo ze-d-aminoacids, ezifana ne-D-serine, i-D-aspartic acid (D-Asp), kunye ne-D-glutamicacid (D-Glu) zifumaneka ngokubanzi kwizilwanyana ezanyisayo kuquka nabantu kwaye ngoku kucingelwa ukuba zingabaviwa benoveli esebenzayo ngokwasemzimbeni. izinto kunye/okanye ii-biomarkers.I-D-[Asp/Glu] (4mg/mL) inqanda ukubopha kwe-IgE (75%) kumandongomane ngelixa i-D-Glu, i-D-Asp ayinayo i-inhibitory effect.I-IgE yeyodwa ye-D-[Asp/Glu] kwaye inokuba namandla okususa i-IgE okanye yokunciphisa i-IgE ebophelelayo kwizinto ezimele zepeanut.

I-D-glutamicacid okwangoku iqwalaselwa njengemodyuli yokudluliselwa kwe-neuronal kunye ne-hormone secretion.Imetabolism kuphela yi-D-aspartate oxidase kwizilwanyana ezanyisayo.Emva kwesitofu se-intraperitoneal, i-L-glutamate yenziwa i-catabolized nge-a-ketoglutarate, ngelixa i-D-glutamate iguqulwa ibe yi-n-pyrrolidone carboxylic acid.I-Carbon2 ye-D- kunye ne-L-glutamate iguqulwa kwi-cecum kwi-methyl carbon ye-acetate.Zombini isibindi segundane kunye nezintso zibangela ukuguqulwa kwe-D-glutamicacid kwi-n-pyrrolidone carboxylic acid.

iimveliso ezinxulumene

L-Nval-OH	Fmoc-N-Me-L-Nval-OH
Fmoc-D-NvaL-OH	I-Boc-Nval-OH
I-Boc-D-Nval-OH	I-Boc-D-Nval-DCHA

Ukongama

1. Inkonzo yeR&D iyafumaneka
2. Umvelisi oqinisekisiweyo we-ISO, isiqinisekiso somgangatho
I-3.Ikhosi epheleleyo yenkonzo yokulandelela ngexesha lemveliso
4.Ixabiso eliphezulu elisebenzayo
5.Amaxwebhu esiqinisekiso somgangatho anikwe ngokwesicelo somthengi
I-6.Inkonzo enkulu emva kokuthengisa, ukugcina ubudlelwane obusondeleyo kunye nomthengi
I-7.Isixhobo esipheleleyo sokunceda ukunciphisa iindleko zokuthumela ngenqanawa
I-8.Isampuli yamahhala enikezelwa ukujonga umgangatho ngaphambi kwayo nayiphi na intlawulo
9.Ixesha lentlawulo ekuxoxwe ngalo
Abathengi be-10.Assit bajongana nemicimbi yaseTshayina