iphepha_ibhena

40216-83-9 H-Hyp-Ome·HCl

40216-83-9 H-Hyp-Ome·HCl

Inkcazelo emfutshane:

Imbonakalo Umgubo omhlophe
MF I-C6H12ClNO3
MW 181.62
Ubunyulu 98+


Iinkcukacha zeMveliso

Imeko yezothutho
Inokuba kubushushu obuqhelekileyo

Cebisa indlela yokuthumela ngenqanawa
Ngomoya Ngomhlaba Ngolwandle

Imeko yokugcina:
Gcina kwindawo emnyama, umoya ongena ngaphakathi, ubushushu begumbi

Beka ubomi kwishelufa
Malunga neminyaka emi-2

Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)

Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]D20                      

Siza kuthumela nayiphi na idatha oyifunayo.Ungayibona idatha ngaphambili njengereferensi.

Kwiimveliso ezilungiselelwe wena, sithumela eyona datha intsha emva kokuba iphumile.

I-D-Ls(tfa)-NCA (2)

Izithethantonye

H-HYP-OMEHCL;
I-HL-HYP-OMEHCL;
I-HYDROXYPROLINE-OMEHCL;
(2S, 4R) -trans-4-hydroxy-L-prolinemethylesterhydrochloride;
I-4-hydroxy-2-pyrrolidinecarboxylicacidmethylesterhydrochloride;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDE;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDESALT;
L-4-TRANS-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDE

Ukupakishwa kwangaphakathi

Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.

Ukupakisha kwangaphakathi 2
Ukupakisha kwangaphakathi 1
Ukupakisha kwangaphakathi 3

ukupakisha kwangaphandle

I-1kg ukuya kwi-25kg Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.

Ukupakisha kwangaphandle 3
Ukupakisha kwangaphandle 2
Ukupakisha kwangaphandle 1

Usetyenziso

Isebenzisa: I-H-Hyp-OMe·HCl isebenza njenge-ADC engenakuqhawulwa (i-antibody-drug conjugate) ikhonkco yokudibanisa i-ADCs.Ii-ADCs, ezenziwe nge-antibody kunye ne-cytotoxin edityaniswe nge-ADC linker, yenza ukuba ukuhanjiswa okuchanekileyo kwee-cytotoxins kwiiseli ezijoliswe kuzo, ngaloo ndlela kunyanga izifo ezithile.Ukongezelela, i-H-Hyp-OMe · HCl yi-PROTAC (iprotein degradation ejolise kwi-chimera) ikhonkco esekelwe kwiintambo ze-alkyl, ezisetyenziswe kwi-synthesis ye-PROTAC.I-PROTACs, equlethe ii-ligands ezimbini ezihlukeneyo ezidibaniswe yi-linker, sebenzisa inkqubo ye-ubiquitin-proteasome yeselula ukukhetha ukuthotywa kweeprotheni ezijoliswe kuyo.

Iipropati: I-H-Hyp-OMe·HCl ngumgubo omhlophe okanye otyheli kancinane we-amorphous onyibilika kwizinyibilikisi ezifana namanzi, i-methanol, kunye ne-ethanol.Ibonisa ukuzinza okulungileyo kunye ne-biocompatibility, ukugcina umsebenzi wayo kunye nokuzinza phantsi kweemeko ze-physiological.

Ngokubanzi, i-H-Hyp-OMe·HCl idlala indima ebalulekileyo ekudityanisweni kwee-ADCs kunye nee-PROTAC njengesixhobo esibalulekileyo se-biochemical reagent kunye nesixhobo sophuhliso lweziyobisi.Ibonelela ngeendlela ezintsha kunye neendlela zokunyanga izifo.Njengoko uphando luqhubeka kwaye iteknoloji iguquka, amathuba okusetyenziswa kwe-H-Hyp-OMe · HCl kulindeleke ukuba abe banzi.

iimveliso ezinxulumene

L-Hyp-OH HL-Hyp-Ome·HCl
HL-Hyp-Oet.HCl L-Hyp-Obzl.Hcl
I-Boc-L-Hyp-OH Boc-L-Hyp-Ome
Fmoc-L-Hyp-Ome Boc-L-Hyp-oet
Fmoc-L-Hyp-OH Fmoc-L-Hyp(tbu)-OH
Cbz-L-Hyp-OH Cbz-L-Hyp-OMe

Ukongama

1. Sinikezela ngokwezifiso iimveliso ozifunayo.
2. Umgangatho ophezulu kunye nexabiso elikhuphisanayo linokubonelelwa.
3. Sithembisa ikhosi epheleleyo yokulandelela inkonzo yakho.
4. Ikhweshine yomthengisi kunye namaxwebhu obugcisa anokubonelelwa ukuba kucelwe emva kokudibana nesixa esithile.
5. Inkonzo enkulu emva kokuthengisa okanye isiqinisekiso : Nawuphi na umbuzo wakho ungasonjululwa ngokukhawuleza.
6. Ukuthengisa ngaphandle iimveliso ezikhuphisanayo kwaye uzithumele kumazwe angaphandle ngobuninzi obukhulu minyaka le.
7. Isampuli yamahhala enikezelwa ukujonga umgangatho ngaphambi kwayo nayiphi na intlawulo.


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