I-China 294855-91-7 Pal-Glu (OSU)-OH uMvelisi kunye neFactory |Jiayinglai

294855-91-7 Pal-Glu (OSU)-OH

Inkcazelo emfutshane:

Imbonakalo	Umgubo omhlophe ukuya kumhlophe
MF	I-C25H42N2O7
MW	482.61
Ubunyulu	98+

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Imeko yezothutho
Inokuba kubushushu obuqhelekileyo

Cebisa indlela yokuthumela ngenqanawa
Ngomoya Ngomhlaba Ngolwandle

Imeko yokugcina:
Gcina kwindawo emnyama, umoya ongena ngaphakathi, ubushushu begumbi

beka ubomi kwishelufa
Malunga neminyaka emi-2

Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)

Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]_D²⁰

Siza kuthumela nayiphi na idatha oyifunayo.Ungayibona idatha ngaphambili njengereferensi.

Kwiimveliso ezilungiselelwe wena, sithumela eyona datha intsha emva kokuba iphumile.

Izithethantonye

iLiraglutidechain;

I-Pal-Glu (OSu)-OH;

iLiraglutideintermediate;

(S) -5-((2,5-dioxopyrrolidin-1-yl) oxy) -5-oxo-2-palmitamidopentanoicacid;

(S) -5-((2,5-dioxopyrrolidin-1-yl) oxy) -2-palmitamidopentanoicacid;

(S)-5-((2,5-dioxopyrrolidin-1-yl)oxy)-5-oxo-2-palm;L-Glutamicacid,N-(1-oxohexadecyl)-,5-(2,5-dioxo -1-pyrrolidinyl)ester;

I-Nα-Palmitoyl-(L)-glutamicacid-γ-succinimidyl-α-tert-butylester

Ukupakishwa kwangaphakathi

Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.

ukupakisha kwangaphandle

I-1kg ukuya kwi-25kg Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.

Usetyenziso

I-Pal-Glu (OSU) -OH, ekwabizwa ngokuba yi-liraglutide side chain, iyikhompawundi ebalulekileyo yeekhemikhali ezinoluhlu olubanzi lwezicelo kwiinkalo ezahlukeneyo.

Okokuqala, kwiinkalo ze-bioscience kunye neyeza, i-Pal-Glu (OSU) -OH isetyenziswe njengekhonkco lecala le-glucagon-like peptide-1 (GLP-1) i-receptor agonists.I-GLP-1 receptor agonists idlala indima ebalulekileyo kuphando lwe-2 yeswekile.Ngokuzibophelela kwi-endogenous metabolic hormone GLP-1, ezi agonists zivuselela ukukhutshwa kwe-insulin kwaye zinqande ukukhutshwa kweglucagon, ngaloo ndlela zinceda kulawulo lwamanqanaba eswekile yegazi.Ngenxa yoko, i-Pal-Glu (OSU)-OH ibamba ixabiso elibalulekileyo ekuphuhliseni unyango lwesifo sikashukela.

Okwesibini, i-Pal-Glu (OSU)-OH iphinda isetyenziswe njengento ekrwada yamachiza e-polypeptide esebenza ixesha elide.Iimpawu zayo ezizodwa zeekhemikhali ziyenza ikwazi ukuthatha inxaxheba ekwakhiweni kwezakhiwo zepeptide ezinemisebenzi ethile yebhayoloji, ibonelela ngamathuba amatsha oyilo nophuhliso lwamachiza.La machiza e-polypeptide anezicelo ezinokubakho kunyango lwezifo ezahlukeneyo.

Ngaphezu koko, i-Pal-Glu (OSU) -OH inokuqeshwa ekulungiseleleni ezinye iikhompawundi ezinemisebenzi ethile.Ngenxa yamaqela ayo asebenzayo kunye neempawu ezisebenzayo, isebenza njengeyona nto ibalulekileyo ephakathi kwi-synthesis yeemolekyuli eziyinkimbinkimbi, ukwandisa ngakumbi ukusetyenziswa kwayo kwikhemistri, isayensi yezinto eziphathekayo, kunye nezinye iinkalo ezinxulumene nazo.

Kutheni Khetha Thina

1. Malunga ne-MOQ: Sinokuyilungisa ngokwemfuno yakho.
2. Malunga nesampuli: Isampuli idinga umrhumo wesampuli, onokuthi ube yimpahla yokuqokelela okanye unokuhlawula kuthi kwangaphambili.
3. Iworkshop yokungunda, ingenziwa ngokwezifiso ngokwenani leemodeli.
4. Sinikezela ngeyona nkonzo ibalaseleyo.Iqela lokuthengisa elinamava sele lisebenzela wena.
5. Malunga notshintshiselwano: Nceda uthumele i-imeyile okanye uxoxe nam ngokufanelekileyo.

Ngaphambili: 2460751-66-8 Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH

Okulandelayo: 323587-47-9 (2S)-2-Amino-3-(tert-butoxy)propanamide hydrochloride

Bhala umyalezo wakho apha kwaye uwuthumele kuthi