INCWADANA YEENDABA
Ngemibuzo malunga neemveliso zethu okanye uluhlu lwamaxabiso, nceda ushiye i-imeyile yakho kuthi kwaye siya kuqhagamshelana phakathi kweeyure ezingama-24.
BUZA NGOKUImeko yezothutho&ecetyiswayo indlela yokuthumela ngenqanawa:
ngomoya, ngolwandle okanye nge-express
Imeko yokugcina:
Ivalwe kwindawo eyomileyo,2-8°C
Ubuncinci boMyinge woMyalelo:
Uthethathethwano
Isiqinisekiso:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC iyafumaneka
FMOC-TYR(ME)-OH;
Fmoc-4-Methoxy-L-Phe-OH;
iMethoxy phenylalanine;
N-FMoc-4-Methoxy-L-phenylalanine, 95%;FMoc-Tyr(Me)-OH;
I-FMoc-O-Methyl-L-tyrosine;
FMOC-(S)-b-(p-Methoxyphenyl)alanine;(S)-2-((((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(4Methoxyphenyl)propanoic acid;
N-Fmoc-O-methyl-L-tyrosine, > = 99%;
Fmoc-4-Methoxy-Phe
Ngokuqhelekileyo zisetyenziselwa ukupakisha umgubo.Yaye anokuthintela ukukhanya kwelanga namanzi ukuba angabi mabi.
Ibhokisi elukhuni inokukhusela iimveliso zakho ekuqhekekeni kwaye zibe manzi.
Inaliti ye-Cabetin, i-cabetin isetyenziswa emva kwe-epidural okanye i-lumbar anesthesia caesarean section ukuthintela ubuthathaka bokufinyela kwesibeleko kunye nokopha kwasemva kokubeleka.Ukusetyenziswa kwe-capectin akuzange kufundwe kwi-caesarean section engxamisekileyo, icandelo le-classical caesarean, i-epidural okanye enye icandelo lotyando phantsi kwe-anesthesia, okanye kwiimeko apho umfazi unembali yesifo senhliziyo, uxinzelelo lwegazi, isifo se-clotting eyaziwayo, okanye isibindi, izintso kunye izifo ze-endocrine (ngaphandle kwesifo sikashukela sokukhulelwa).Unyango nge-capetin emva kokubeleka kwelungu lobufazi alukhange lufundwe ngokufanelekileyo kwaye nedosi ayikamiselwa.
I-Carbetin isetyenziswe emva kwecandelo le-epidural okanye i-lumbar anesthesia caesarean section ukuthintela ubuthathaka be-uterine contraction kunye nokopha emva kokubeleka.
Ukusetyenziswa kwe-capectin akuzange kufundwe kwi-caesarean section engxamisekileyo, icandelo le-classical caesarean, i-epidural okanye enye icandelo lotyando phantsi kwe-anesthesia, okanye kwiimeko apho umfazi unembali yesifo senhliziyo, uxinzelelo lwegazi, isifo se-clotting eyaziwayo, okanye isibindi, izintso kunye izifo ze-endocrine (ngaphandle kwesifo sikashukela sokukhulelwa).Unyango nge-capetin emva kokubeleka kwelungu lobufazi alukhange lufundwe ngokufanelekileyo kwaye nedosi ayikamiselwa.
Idosi enye ye-100 micrograms (1 ml) ye-capetin inikezelwa nge-intravenously kwaye ngokukhawuleza kuphela kwi-dose enye ye-1 ngomzuzu emva kokuba umntwana ebelethwe ngotyando phantsi kwe-epidural okanye i-lumbar anesthesia.I-Cabetin inokunikwa ngaphambi okanye emva kokubeleka kwe-placenta, okanye njengoko kuyalelwa ngugqirha.
Xa kuthelekiswa ne-oxytocin, iimpembelelo ze-cabetin zithatha ixesha elide, kwaye iziphumo ze-contraction ze-uterine azikwazi ukumiswa nje ngokuyeka ichiza.Ngoko ke, i-carpeine ayifanele inikwe ngaphambi kokunikezelwa ngenxa yaso nasiphi na isizathu, kubandakanywa ukuveliswa okukhethiweyo okanye okwenziwa ngamachiza.Ukusetyenziswa ngokungafanelekanga kwe-capetin ngexesha lokukhulelwa kunokuvelisa iimpawu ezifana nezo ze-oxytocin overdose, ezi ziquka ukuxinwa okunamandla (hypertonic) kunye nokuqhubekayo (i-tonic) emva kokuphazamiseka kwe-uterine hyperstimulation, ukuphazamiseka ngexesha lokubeleka, ukuphuka kwesibeleko, umlomo wesibeleko kunye neenyembezi ze-vaginal, i-postpartum hemorrhage, ukuncipha kwe-uterine. -igazi le-placental kunye nokwehla kwentliziyo yomntwana, ukunqongophala kweoksijini yomntwana, i-hypercapnia, kunye nokufa.
I-Capetin akufanele isetyenziswe kwizigulane ezingadibaniyo ne-oxytocin kunye ne-capetin.
I-Carbetin ayifanele isetyenziswe kwizigulane ezine-vascular disease, ngakumbi isifo se-coronary artery, kodwa kufuneka isetyenziswe ngokuqaphela okukhulu.
ICapetin nayo ayifanele ukusetyenziswa ebantwaneni.
Boc-Gly-Tyr-OH | Boc-Tyr-Otbu | L-Tyr(mna).Hcl | Fmoc-D-Tyr(Et)-D-Tyr(Et) |
Boc-Gly-Tyr-OMe | Boc-D-Tyr-Otbu | D-Tyr(bzl).Hcl | Fmoc-D-Tyr(tbu)-OH |
Gly-L-Tyr-OH | Boc-DL-Tyr-Otbu | D-Tyr(Et).HCl | Cbz-L-Tyr-OH |
Gly-L-Tyr-OH | Boc-L-Tyr-Obzl | L-Tyr(bzl)-obzl.Hcl | Cbz-D-Tyr-OH |
Fmoc-β-Ala-D-Tyr (Et) | I-Boc-L-Tyr(tBu)-OH | L-Tyr(tbu)-OH | Cbz-N-Me-Tyr(tbu)-OH |
Val-Tyr-OH | Boc-Tyr(bzl)-OH | L-Tyr-OL.Hcl | cbz-L-Tyr-Ome |
Cbz-L-Val-Tyr-OH | Boc-D-Tyr(bzl)-OH | D-Tyr-Ome.Hcl | Cbz-L-Tyr(Et)-OH |
Cbz-L-Val-Tyr-Ome | Boc-L-Tyr(mna)-OH | L-Tyr(bzl)-Ome.Hcl | Z-Tyr(tbu) |
Ile-Tyr | Boc-D-Tyr(mna)-OH | L-Tyr-Oet-OH | Z-Tyr(bzl)-OH |
Boc-Ile-Tyr | Boc-Tyr (kodwa).Aib | D-Tyr-Oet•HCl | Z-Tyr(tbu).DCHA |
Tyr-Pro-Otbu | Fmoc-L-Tyr-OH | L-Tyr-Ome.HCl | Tyr-Phe |
L-Phe-Tyr-OH | Fmoc-N-Me-Tyr(tBu)-OH | HL-Tyr-Oet.Hcl | Tyr-Asp |
Boc-L-Phe-Tyr-OH | FMOC-N-Me-D-Tyr(me)-OH | Ac-D,L-Tyr-OH | Arg-Tyr-Oet |
L-Tyr-OH | Fmoc-N-Me-D-Tyr(tBu)-OH | AC-L-Tyr-OH | Cbz-L-Ser-Tyr |
D-Tyr-OH | Fmoc-N-Me-L-Tyr(bzl)-OH | N-Ac-L-Tyr-Oet | Tyr(bzl)-obzl |
DL-Tyr | Fmoc-L-Tyr-Ome | L-Tyr-Otbu | Boc-L-Tyr(Et)-OH |
N-Me-Tyr(mna)-OH | Fmoc-L-Tyr(Cbz) | D-Tyr-Otbu | Boc-D-Tyr(Et)-OH |
N-Me-Tyr(mna).HCL | Fmoc-L-Tyr(bzl)-oh | L-Tyr-Obzl | Boc-N-Me-L-Tyr(bzl)-OH |
L-Tyr-NCA | Fmoc-L-Tyr(Et)-OH | L-Tyr-obzl-Tos-OH | Boc-N-Me-D-Tyr(bzl)-OH |
D-Tyr-NCA | Fmoc-L-Tyr(tBu)-OH | Boc-L-Tyr-OH | Boc-N-Me-L-Tyr(tbu)-OH |
Tyr(bzl)-NCA | Fmoc-L-Tyr(mna) | Boc-D-Tyr-OH | Boc-L-Tyr-OL |
Tyr(bzl)-NCA | Fmoc-L-Tyr(mna)-tyr(mna) | Boc-DL-Tyr-OH | Boc-D-Tyr(bzl)-OL |
L-Tyr(Et)-OH | Fmoc-D-Tyr(mna)-OH | Boc-L-Tyr-Oet | Boc-L-Tyr(bzl)-Ol |
L-Tyr(mna) | Fmoc-D-Tyr(Et)-OH | Boc-L-Tyr-Ome | Boc-L-Tyr(me)-OL |
1. Inkonzo yeR&D iyafumaneka
2. Umvelisi oqinisekisiweyo we-ISO, isiqinisekiso somgangatho
I-3.Ikhosi epheleleyo yenkonzo yokulandelela ngexesha lemveliso
4.Ixabiso eliphezulu elisebenzayo
5.Amaxwebhu esiqinisekiso somgangatho anikwe ngokwesicelo somthengi
I-6.Inkonzo enkulu emva kokuthengisa, ukugcina ubudlelwane obusondeleyo kunye nomthengi
I-7.Isixhobo esipheleleyo sokunceda ukunciphisa iindleko zokuthumela ngenqanawa
I-8.Isampuli yamahhala enikezelwa ukujonga umgangatho ngaphambi kwayo nayiphi na intlawulo
9.Ixesha lentlawulo ekuxoxwe ngalo
Abathengi be-10.Assit bajongana nemicimbi yaseTshayina