I-China 77128-72-4 Fluorene methoxy carbonyl-L-tyrosine(methyl) uMvelisi kunye neFactory |Jiayinglai

77128-72-4 Fluorene methoxy carbonyl-L-tyrosine(methyl)

Inkcazelo emfutshane:

Imbonakalo	Iikristale eziMhlophe ukuya kwi-Off-White okanye umgubo wekristale.
MF	C25H23NO5
MW	417.45
Ubunyulu	98+

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Imeko yezothutho&ecetyiswayo indlela yokuthumela ngenqanawa:
ngomoya, ngolwandle okanye nge-express

Imeko yokugcina:
Ivalwe kwindawo eyomileyo,2-8°C

Ubuncinci boMyinge woMyalelo:
Uthethathethwano

Isiqinisekiso:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC iyafumaneka

Izithethantonye

FMOC-TYR(ME)-OH;
Fmoc-4-Methoxy-L-Phe-OH;
iMethoxy phenylalanine;
N-FMoc-4-Methoxy-L-phenylalanine, 95%;FMoc-Tyr(Me)-OH;
I-FMoc-O-Methyl-L-tyrosine;
FMOC-(S)-b-(p-Methoxyphenyl)alanine;(S)-2-((((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(4Methoxyphenyl)propanoic acid;
N-Fmoc-O-methyl-L-tyrosine, > = 99%;
Fmoc-4-Methoxy-Phe

Ukupakishwa kwangaphakathi

Ngokuqhelekileyo zisetyenziselwa ukupakisha umgubo.Yaye anokuthintela ukukhanya kwelanga namanzi ukuba angabi mabi.

ukupakisha kwangaphandle

Ibhokisi elukhuni inokukhusela iimveliso zakho ekuqhekekeni kwaye zibe manzi.

Usetyenziso

Inaliti ye-Cabetin, i-cabetin isetyenziswa emva kwe-epidural okanye i-lumbar anesthesia caesarean section ukuthintela ubuthathaka bokufinyela kwesibeleko kunye nokopha kwasemva kokubeleka.Ukusetyenziswa kwe-capectin akuzange kufundwe kwi-caesarean section engxamisekileyo, icandelo le-classical caesarean, i-epidural okanye enye icandelo lotyando phantsi kwe-anesthesia, okanye kwiimeko apho umfazi unembali yesifo senhliziyo, uxinzelelo lwegazi, isifo se-clotting eyaziwayo, okanye isibindi, izintso kunye izifo ze-endocrine (ngaphandle kwesifo sikashukela sokukhulelwa).Unyango nge-capetin emva kokubeleka kwelungu lobufazi alukhange lufundwe ngokufanelekileyo kwaye idosi ayikamiselwa.
I-Carbetin isetyenziswe emva kwecandelo le-epidural okanye i-lumbar anesthesia caesarean section ukuthintela ubuthathaka be-uterine contraction kunye nokopha emva kokubeleka.
Ukusetyenziswa kwe-capectin akuzange kufundwe kwi-caesarean section engxamisekileyo, icandelo le-classical caesarean, i-epidural okanye enye icandelo lotyando phantsi kwe-anesthesia, okanye kwiimeko apho umfazi unembali yesifo senhliziyo, uxinzelelo lwegazi, isifo se-clotting eyaziwayo, okanye isibindi, izintso kunye izifo ze-endocrine (ngaphandle kwesifo sikashukela sokukhulelwa).Unyango nge-capetin emva kokubeleka kwelungu lobufazi alukhange lufundwe ngokufanelekileyo kwaye idosi ayikamiselwa.
Idosi enye ye-100 micrograms (1 ml) ye-capetin inikezelwa nge-intravenously kwaye ngokukhawuleza kuphela kwi-dose enye ye-1 ngomzuzu emva kokuba umntwana ebelethwe ngotyando phantsi kwe-epidural okanye i-lumbar anesthesia.I-Cabetin inokunikwa ngaphambi okanye emva kokubeleka kwe-placenta, okanye njengoko kuyalelwa ngugqirha.
Xa kuthelekiswa ne-oxytocin, iimpembelelo ze-cabetin zithatha ixesha elide, kwaye iziphumo ze-contraction ze-uterine azikwazi ukumiswa nje ngokuyeka ichiza.Ngoko ke, i-carpeine ayifanele inikwe ngaphambi kokunikezelwa ngenxa yaso nasiphi na isizathu, kubandakanywa ukuveliswa okukhethiweyo okanye okwenziwa ngamachiza.Ukusetyenziswa ngokungafanelekanga kwe-capetin ngexesha lokukhulelwa kunokuvelisa iimpawu ezifana nezo ze-oxytocin overdose, ezi ziquka ukuxinwa okunamandla (hypertonic) kunye nokuqhubekayo (i-tonic) emva kokuphazamiseka kwe-uterine hyperstimulation, ukuphazamiseka ngexesha lokubeleka, ukuphuka kwesibeleko, umlomo wesibeleko kunye neenyembezi ze-vaginal, i-postpartum hemorrhage, ukuncipha kwe-uterine. -igazi le-placental kunye nokwehla kwentliziyo yomntwana, ukunqongophala kweoksijini yomntwana, i-hypercapnia, kunye nokufa.
I-Capetin akufanele isetyenziswe kwizigulane ezingadibaniyo ne-oxytocin kunye ne-capetin.
I-Carbetin ayifanele isetyenziswe kwizigulane ezine-vascular disease, ngokukodwa isifo se-coronary artery, kodwa kufuneka isetyenziswe ngononophelo olukhulu.
ICapetin nayo ayifanele ukusetyenziswa ebantwaneni.

iimveliso ezinxulumene

Boc-Gly-Tyr-OH	Boc-Tyr-Otbu	L-Tyr(mna).Hcl	Fmoc-D-Tyr(Et)-D-Tyr(Et)
Boc-Gly-Tyr-OMe	Boc-D-Tyr-Otbu	D-Tyr(bzl).Hcl	Fmoc-D-Tyr(tbu)-OH
Gly-L-Tyr-OH	Boc-DL-Tyr-Otbu	D-Tyr(Et).HCl	Cbz-L-Tyr-OH
Gly-L-Tyr-OH	Boc-L-Tyr-Obzl	L-Tyr(bzl)-obzl.Hcl	Cbz-D-Tyr-OH
Fmoc-β-Ala-D-Tyr (Et)	I-Boc-L-Tyr(tBu)-OH	L-Tyr(tbu)-OH	Cbz-N-Me-Tyr(tbu)-OH
Val-Tyr-OH	Boc-Tyr(bzl)-OH	L-Tyr-OL.Hcl	cbz-L-Tyr-Ome
Cbz-L-Val-Tyr-OH	Boc-D-Tyr(bzl)-OH	D-Tyr-Ome.Hcl	Cbz-L-Tyr(Et)-OH
Cbz-L-Val-Tyr-Ome	Boc-L-Tyr(mna)-OH	L-Tyr(bzl)-Ome.Hcl	Z-Tyr(tbu)
Ile-Tyr	Boc-D-Tyr(mna)-OH	L-Tyr-Oet-OH	Z-Tyr(bzl)-OH
Boc-Ile-Tyr	Boc-Tyr (kodwa).Aib	D-Tyr-Oet•HCl	Z-Tyr(tbu).DCHA
Tyr-Pro-Otbu	Fmoc-L-Tyr-OH	L-Tyr-Ome.HCl	Tyr-Phe
L-Phe-Tyr-OH	Fmoc-N-Me-Tyr(tBu)-OH	HL-Tyr-Oet.Hcl	Tyr-Asp
Boc-L-Phe-Tyr-OH	FMOC-N-Me-D-Tyr(me)-OH	Ac-D,L-Tyr-OH	Arg-Tyr-Oet
L-Tyr-OH	Fmoc-N-Me-D-Tyr(tBu)-OH	AC-L-Tyr-OH	Cbz-L-Ser-Tyr
D-Tyr-OH	Fmoc-N-Me-L-Tyr(bzl)-OH	N-Ac-L-Tyr-Oet	Tyr(bzl)-obzl
DL-Tyr	Fmoc-L-Tyr-Ome	L-Tyr-Otbu	Boc-L-Tyr(Et)-OH
N-Me-Tyr(mna)-OH	Fmoc-L-Tyr(Cbz)	D-Tyr-Otbu	Boc-D-Tyr(Et)-OH
N-Me-Tyr(mna).HCL	Fmoc-L-Tyr(bzl)-oh	L-Tyr-Obzl	Boc-N-Me-L-Tyr(bzl)-OH
L-Tyr-NCA	Fmoc-L-Tyr(Et)-OH	L-Tyr-obzl-Tos-OH	Boc-N-Me-D-Tyr(bzl)-OH
D-Tyr-NCA	Fmoc-L-Tyr(tBu)-OH	Boc-L-Tyr-OH	Boc-N-Me-L-Tyr(tbu)-OH
Tyr(bzl)-NCA	Fmoc-L-Tyr(mna)	Boc-D-Tyr-OH	Boc-L-Tyr-OL
Tyr(bzl)-NCA	Fmoc-L-Tyr(mna)-tyr(mna)	Boc-DL-Tyr-OH	Boc-D-Tyr(bzl)-OL
L-Tyr(Et)-OH	Fmoc-D-Tyr(mna)-OH	Boc-L-Tyr-Oet	Boc-L-Tyr(bzl)-Ol
L-Tyr(mna)	Fmoc-D-Tyr(Et)-OH	Boc-L-Tyr-Ome	Boc-L-Tyr(me)-OL

Ukongama

1. Inkonzo yeR&D iyafumaneka
2. Umvelisi oqinisekisiweyo we-ISO, isiqinisekiso somgangatho
I-3.Ikhosi epheleleyo yenkonzo yokulandelela ngexesha lemveliso
4.Ixabiso eliphezulu elisebenzayo
5.Amaxwebhu esiqinisekiso somgangatho anikwe ngokwesicelo somthengi
I-6.Inkonzo enkulu emva kokuthengisa, ukugcina ubudlelwane obusondeleyo kunye nomthengi
I-7.Isixhobo esipheleleyo sokunceda ukunciphisa iindleko zokuthumela ngenqanawa
I-8.Isampuli yamahhala enikezelwa ukujonga umgangatho ngaphambi kwayo nayiphi na intlawulo
9.Ixesha lentlawulo ekuxoxwe ngalo
Abathengi be-10.Assit bajongana nemicimbi yaseTshayina