Iindlela eziqhelekileyo zokukhusela i-amino

1. Cbz
I-Benzyloxycarbonyl (Cbz) i-Amino ekhuselweyo
Ukukhuselwa kwe-N-benzyloxycarbonyl (Cbz)
Ii-reagents ezisetyenziswa ngokuqhelekileyo - CbzCl

2. I-alloc
I-Allyloxycarbonyl (Alloc) iqela le-amino elikhuselweyo

3. I-Trifluoroacetyl
Iqela le-amino elikhuselweyo le-Trifluoroacetyl

4. Iibenzils
p-methoxybenzyl (PMB) ekhuselweyo iqela amino
I-2,4-dimethoxybenzyl ekhuselweyo iqela le-amino
I-Benzyl ikhuselwe i-amino
Ukukhuselwa kweqela le-amino elikhuselwe yi-benzyl
N-Bn debenzylation ngendlela chloroformate

5. Pht (phthaloyl)
I-Phthaloyl (Pht) ikhuselwe amaqela e-amino
Ukukhuselwa kweqela le-amino elikhuselwe yiphthaloyl

6. Benzenesulfonyl
I-Nitrobenzenesulfonyl ekhuselweyo iqela le-amino
p-toluenesulfonyl (Tos) ukhuseleko lwe-amino

7. Trt
I-Trityl ikhuselwe i-amino
Ukukhuselwa kweqela le-amino elikhuselwe nge-trityl

8. Boc
Iqela le-amino elikhuselweyo iTert-butoxycarbonyl
Ukukhuselwa kwe-N-tert-butoxycarbonyl
Oxalyl Chloride De-Boc

9. Fmoc
I-Wat methoxycarbonyl ekhuselweyo kwiqela le-amino
Ii-reagents ezisetyenziswa ngokuqhelekileyo - Fmoc-Cl

10. I-SEM
I-SEM ikhuselwe amino

11. Abanye
I-Acetamide ikhuselwe iqela le-amino
I-Clauson-Kaas pyrrole synthesis reaction (le mpendulo ingasetyenziswa njengendlela yokukhusela amaqela e-amino, inokubuyisela ukhuseleko lwe-Boc kabini, kwaye izinzile)
Ii-reagents ezisetyenziswa ngokuqhelekileyo - i-benzyl (chloromethyl) ether
Iirejenti ezisetyenziswa ngokuqhelekileyo - (chloromethyl) methyl ether [MOMCl]
Ukukhuselwa kweCarbamate