I-China 166108-71-0 Fmoc-AEEA-OH uMvelisi kunye neFactory |Jiayinglai

166108-71-0 Fmoc-AEEA-OH

Inkcazelo emfutshane:

Imbonakalo	Umgubo omhlophe ukuya kumhlophe
MF	C21H23NO6
MW	385.41
Ubunyulu	98+

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Imeko yezothutho
Inokuba kubushushu obuqhelekileyo

Cebisa indlela yokuthumela ngenqanawa
Ngomoya Ngomhlaba Ngolwandle

Imeko yokugcina:
Gcina kwindawo emnyama, umoya ongena ngaphakathi, ubushushu begumbi

beka ubomi kwishelufa
Malunga neminyaka emi-2

Ubuncinci uMyalelo weQty:
1kg (uthethathethwano)

Isiqinisekiso:COA, indawo yokunyibilika, iSpecificRotation [α]_D²⁰

Siza kuthumela nayiphi na idatha oyifunayo.Ungayibona idatha ngaphambili njengereferensi.

Kwiimveliso ezilungiselelwe wena, sithumela eyona datha intsha emva kokuba iphumile.

Izithethantonye

[2- [2-(Fmoc-amino) ethoxy]ethoxy]acetic acid

I-Fmoc-8-amino-3,6-dioxaoctanoic acid, i-Fmoc-AEEA

I-Fmoc-PEG2-acetic acid

{2-[2-(Fmoc-amino) ethoxy]ethoxy}acetic acid≥ 99% (HPLC)

I-Fmoc-NH-(PEG)-COOH (i-athomu ezili-9) Novabiochem

1-(9H-Fluoren-9-yl)-3-oxo-2,7,1-trioxa-4-azadodecan-12-oic acid

I-9-FLUORENYLMETHOXYCARBONYL-8-AMINO-3,6-DIOXAOCTANOIC ACID

8-(FMOC-AMINO)-3,6-DIOXA-OCTANOIC ACID

I-8-FLUORENYLMETHOXYCARBONYLAMINO-3,6-DIOXAOCTANOIC ACID

Ukupakishwa kwangaphakathi

Zihlala zisetyenziselwa ukupakisha umgubo.Kuxhomekeke kwiimfuno zabathengi.Ke ngoko, sixelele ngemfuno yakho phambi kokupakisha ukuba unezicelo ezizodwa.

ukupakisha kwangaphandle

I-1kg ukuya kwi-25kg Ukupakisha kwangaphandle kunzima.Kwaye kunzima ukusika kunye nomonakalo.Inokukhusela iimveliso zakho ngokugqibeleleyo.

Usetyenziso

I-166108-71-0 I-Fmoc-AEEA-OH sisikhonkco se-ADC esicandekayo esisetyenziswe kwi-synthesis ye-antibody-drug conjugates (ADCs).I-Fmoc-8-amino-3,6-dioxaoctanoic acid nayo i-PEG-based based PROTAC linker enokusetyenziswa kwi-synthesis ye-PROTAC.

166108-71-0 I-Fmoc-AEEA-OH nayo ingaba yenye ye-semaglutide Intermediates.

Impembelelo ephambili ye-semaglutide kukunyanga uhlobo lwe-2 yeswekile ngokunciphisa amanqanaba e-glucose yegazi.Ilinganisa ihomoni efana ne-insulin efana ne-peptide-1, evuselela ukukhutshwa kwe-insulin kwaye inqanda ukukhutshwa kweglucagon, ngaloo ndlela inciphisa amanqanaba eglucose yegazi.I-Semaglutide ayinagalelo kumngcipheko we-hypoglycaemia eyenzekayo xa kuthelekiswa nonyango oluqhelekileyo lwe-insulin kuba indlela yokusebenza kwayo inzima kwaye ichanekile.Ngokulungelelanisa ibhalansi ye-insulin kunye neglucagon, i-somalutide inokunceda abantu abanesifo sikashukela sohlobo lwe-2 balawule ngcono amanqanaba eswekile yegazi.

Ukongeza ekunciphiseni amanqanaba eswekile yegazi, i-semaglutide inokunciphisa ubunzima bomzimba.Oku kungenxa yefuthe layo lokucinezela ukutya.I-semaglutide ivuselela umsebenzi weziko le-satiety kwi-hypothalamus, eyanciphisa ukutya.Inzuzo ephambili ye-semaglutide ngaphezu kwamanye amachiza okulahlekelwa kwesisindo kukuba ilahlekelwa ubunzima ngelixa iphucula ukuxhathisa kwe-insulin kunye nokulawula iswekile yegazi.Oku kuyenza ibe lukhetho olunqwenelekayo lonyango kwizigulana ezinesifo seswekile ngokutyeba.

Ukongezelela, i-semaglutide iphucula umsebenzi we-pancreatic kwaye inciphisa iimpendulo ezivuthayo kwiiseli ze-pancreatic islet.Ikhusela iiseli ze-islet kumonakalo ongakumbi obangelwa sisifo seswekile kwaye ikhuthaza ukuhlaziywa kweeseli ze-islet.Oku kubaluleke kakhulu kubantu abanesifo seswekile se-2, njengoko umonakalo omkhulu we-islet cell unokukhokelela ekungaphumeleli kwe-islet.

Ngokubanzi, i-semaglutide iyeza elisebenzayo kwaye likhuselekile kunyango lwe-2 yeswekile.Inceda izigulana ukulawula kangcono isifo seswekile kunye nokunciphisa iingxaki ngokunciphisa amanqanaba e-glucose yegazi, ukunciphisa ubunzima bomzimba, ukuphucula ukusebenza kwe-islet, kunye nokukhusela iiseli ze-islet.Izifundo zexesha elizayo ziya kuphonononga ngakumbi amandla e-somatostatin kunyango lwezinye izifo, ezifana ne-NAFLD kunye nokukhuluphala.

iimveliso ezinxulumene

Fmoc-AEEA-AEEA-OH

Fmoc-L-Lys(dde)-OH

I-DDE-Ls(Fmoc)-OH

Kutheni Khetha Thina

1. Malunga ne-MOQ: Sinokuyilungisa ngokwemfuno yakho.
2. Malunga nesampuli: Isampuli idinga umrhumo wesampuli, onokuthi ube yimpahla yokuqokelela okanye unokuhlawula kuthi kwangaphambili.
3. Iworkshop yokungunda, ingenziwa ngokwezifiso ngokwenani leemodeli.
4. Sinikezela ngeyona nkonzo ibalaseleyo.Iqela lokuthengisa elinamava sele lisebenzela wena.
5. Malunga notshintshiselwano: Nceda uthumele i-imeyile okanye uxoxe nam ngokufanelekileyo.

Ngaphambili: 68858-20-8 Fmoc-L-Val-OH

Okulandelayo: 15962-47-7 Ac-L-Ala-NH2

Bhala umyalezo wakho apha kwaye uwuthumele kuthi