3060-46-6 N-Me-L-Leu

I-Peptide Synthesis kunye nokuguqulwa: I-N-Me-L-Leu ingasetyenziswa njengebhloko yokwakha kwi-peptide synthesis yesigaba esiqinileyo.Ivumela ukuqaliswa kweqela le-methyl kwindawo ye-nitrogen ye-leucine, enokuguqula iimpawu ze-physicochemical kunye nomsebenzi we-biological we-peptides ephumela.Olu hlengahlengiso lunokomeleza uzinzo lwe-peptide, luguqule unxibelelwano lwayo nezinye iimolekyuli, okanye luphembelele ukujoliswa kweselula.

UPhando lweeProteomics: Kuphononongo lweproteomics, i-N-Me-L-Leu ingasetyenziswa njengesixhobo sokuleyibhile sobungakanani beprotheyini okanye njengophando lokuphanda intsebenziswano yeeprotheyini.Iqela le-methyl linokubonelela ngethegi yobunzima obukhethekileyo obunokubonwa nge-mass spectrometry, eyenza uhlalutyo lobungakanani beeprotheni kwiingxube ezinzima.

Ukufunyanwa kweziyobisi kunye noPhuhliso: I-N-Me-L-Leu inezicelo ezinokubakho ekufumaneni ichiza kunye nophuhliso.Inokufakwa kubaviwa beziyobisi ukulungelelanisa umsebenzi wabo webhayoloji, ukunyibilika, okanye iipropathi ze-pharmacokinetic.Iqela le-methyl linokuchaphazela ubudlelwane obubophelelayo bechiza kwithagethi yalo, liphucule ukufikeleleka kweseli yalo, okanye liguqule ukuzinza kwalo kwe-metabolic.

I-Biological Probes kunye ne-Imaging Agents: I-N-Me-L-Leu inokudityaniswa kwiidayi ze-fluorescent, ii-radiolabels, okanye ezinye iimolekyuli zengxelo ukwenza i-biological probes okanye i-imaging agents.Ezi probes zingasetyenziselwa ukujonga okanye ukulinganisa iinkqubo ezithile zebhayoloji kwiiseli okanye izicubu, ukubonelela ngengqiqo kwimisebenzi yeselula kunye neendlela zokugula.

Izongezo zesondlo: Kwintsimi yesondlo, i-N-Me-L-Leu inokuba namandla njengesongezelelo sesondlo okanye isithako ekutya okusebenzayo.I-Leucine yi-amino acid ebalulekileyo ebandakanyekayo kwiprotheni synthesis kunye ne-muscle metabolism.I-methylated derivative inokubonelela ngeenzuzo ezithile ezinxulumene ne-bioavailability yayo ephuculweyo okanye iziphumo eziguquliweyo ze-metabolic.